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Neratinib protects pancreatic beta cells in diabetes.
Ardestani A, Li S, Annamalai K, Lupse B, Geravandi S, Dobrowolski A, Yu S, Zhu S, Baguley TD, Surakattula M, Oetjen J, Hauberg-Lotte L, Herranz R, Awal S, Altenhofen D, Nguyen-Tran V, Joseph S, Schultz PG, Chatterjee AK, Rogers N, Tremblay MS, Shen W, Maedler K. Ardestani A, et al. Nat Commun. 2019 Nov 1;10(1):5015. doi: 10.1038/s41467-019-12880-5. Nat Commun. 2019. PMID: 31676778 Free PMC article.
Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
Shen W, Taylor B, Jin Q, Nguyen-Tran V, Meeusen S, Zhang YQ, Kamireddy A, Swafford A, Powers AF, Walker J, Lamb J, Bursalaya B, DiDonato M, Harb G, Qiu M, Filippi CM, Deaton L, Turk CN, Suarez-Pinzon WL, Liu Y, Hao X, Mo T, Yan S, Li J, Herman AE, Hering BJ, Wu T, Martin Seidel H, McNamara P, Glynne R, Laffitte B. Shen W, et al. Nat Commun. 2015 Oct 26;6:8372. doi: 10.1038/ncomms9372. Nat Commun. 2015. PMID: 26496802 Free PMC article.
Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant.
Wang RE, Wang Y, Zhang Y, Gabrelow C, Zhang Y, Chi V, Fu Q, Luo X, Wang D, Joseph S, Johnson K, Chatterjee AK, Wright TM, Nguyen-Tran VT, Teijaro J, Theofilopoulos AN, Schultz PG, Wang F. Wang RE, et al. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11501-11506. doi: 10.1073/pnas.1612803113. Epub 2016 Sep 23. Proc Natl Acad Sci U S A. 2016. PMID: 27663736 Free PMC article.
29 results