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143 results

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Page 1
Excess mucus viscosity and airway dehydration impact COPD airway clearance.
Lin VY, Kaza N, Birket SE, Kim H, Edwards LJ, LaFontaine J, Liu L, Mazur M, Byzek SA, Hanes J, Tearney GJ, Raju SV, Rowe SM. Lin VY, et al. Among authors: lafontaine j. Eur Respir J. 2020 Jan 30;55(1):1900419. doi: 10.1183/13993003.00419-2019. Print 2020 Jan. Eur Respir J. 2020. PMID: 31672759 Free PMC article.
Airway remodeling in ferrets with cigarette smoke-induced COPD using µCT imaging.
Stanford D, Kim H, Bodduluri S, LaFontaine J, Byzek SA, Schoeb TR, Harris ES, Nath HP, Bhatt SP, Raju SV, Rowe SM. Stanford D, et al. Among authors: lafontaine j. Am J Physiol Lung Cell Mol Physiol. 2020 Jul 1;319(1):L11-L20. doi: 10.1152/ajplung.00328.2019. Epub 2020 May 6. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32374671 Free PMC article.
Nicotine aerosols diminish airway CFTR function and mucociliary clearance.
Rasmussen LW, Stanford D, LaFontaine J, Allen AD, Raju SV. Rasmussen LW, et al. Among authors: lafontaine j. Am J Physiol Lung Cell Mol Physiol. 2023 May 1;324(5):L557-L570. doi: 10.1152/ajplung.00453.2021. Epub 2023 Feb 28. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 36852921 Free PMC article.
Acute kidney injury results in long-term alterations of kidney lymphatics in mice.
Ghajar-Rahimi G, Barwinska D, Whipple GE, Kamocka MM, Khan S, Winfree S, Lafontaine J, Soliman RH, Melkonian AL, Zmijewska AA, Cheung MD, Traylor AM, Jiang Y, Yang Z, Bolisetty S, Zarjou A, Lee T, George JF, El-Achkar TM, Agarwal A. Ghajar-Rahimi G, et al. Among authors: lafontaine j. Am J Physiol Renal Physiol. 2024 Nov 1;327(5):F869-F884. doi: 10.1152/ajprenal.00120.2024. Epub 2024 Sep 26. Am J Physiol Renal Physiol. 2024. PMID: 39323387
Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer.
Gallego RA, Cho-Schultz S, Del Bel M, Dechert-Schmitt AM, Donaldson JS, He M, Jalaie M, Kania R, Matthews J, McTigue M, Tuttle JB, Risley H, Zhou D, Zhou R, Ahmad OK, Bernier L, Berritt S, Braganza J, Chen Z, Cianfrogna JA, Collins M, Costa Jones C, Cronin CN, Davis C, Dress K, Edwards M, Farrell W, France SP, Grable N, Johnson E, Johnson TW, Jones R, Knauber T, Lafontaine J, Loach RP, Maestre M, Miller N, Moen M, Monfette S, Morse P, Nager AR, Niosi M, Richardson P, Rohner AK, Sach NW, Timofeevski S, Tucker JW, Vetelino B, Zhang L, Nair SK. Gallego RA, et al. Among authors: lafontaine j. J Med Chem. 2024 Dec 26;67(24):22002-22038. doi: 10.1021/acs.jmedchem.4c01930. Epub 2024 Dec 9. J Med Chem. 2024. PMID: 39651809 Clinical Trial.
A Huge Conjunctival Atypical Fibroxanthoma.
Ramirez Marquez E, López-Fontanet JJ, Torres G, Lafontaine J, Correa M, Oliver AL, Campbell J. Ramirez Marquez E, et al. Among authors: lafontaine j. Cureus. 2024 Oct 9;16(10):e71130. doi: 10.7759/cureus.71130. eCollection 2024 Oct. Cureus. 2024. PMID: 39525205 Free PMC article.
Discovery of Highly Selective Inhibitors of Microtubule-Associated Serine/Threonine Kinase-like (MASTL).
Gallego RA, Scales S, Toledo C, Auth M, Bernier L, Berry M, Brun S, Chung L, Davis C, Diehl W, Dress K, Eisele K, Elleraas J, Ewanicki J, Fobian Y, Greasley S, Greenwald EC, Johnson TW, Khamphavong P, Lafontaine J, Li J, Linton A, Maestre M, Miller N, Murtaza A, Patman RL, Quinlan CL, Ramms DJ, Richardson P, Sach N, Salomon-Ferrer R, Silva F, Timofeevski S, Tran P, Tran-Dubé M, Wang F, Wang W, Wythes M, Yang S, Zou A, VanArsdale T, McAlpine I. Gallego RA, et al. Among authors: lafontaine j. J Med Chem. 2024 Nov 14;67(21):19234-19246. doi: 10.1021/acs.jmedchem.4c01659. Epub 2024 Nov 5. J Med Chem. 2024. PMID: 39499084
143 results