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Page 1
Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy.
Vilchez D, Ros S, Cifuentes D, Pujadas L, Vallès J, García-Fojeda B, Criado-García O, Fernández-Sánchez E, Medraño-Fernández I, Domínguez J, García-Rocha M, Soriano E, Rodríguez de Córdoba S, Guinovart JJ. Vilchez D, et al. Among authors: guinovart jj. Nat Neurosci. 2007 Nov;10(11):1407-13. doi: 10.1038/nn1998. Epub 2007 Oct 21. Nat Neurosci. 2007. PMID: 17952067
Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease.
Valles-Ortega J, Duran J, Garcia-Rocha M, Bosch C, Saez I, Pujadas L, Serafin A, Cañas X, Soriano E, Delgado-García JM, Gruart A, Guinovart JJ. Valles-Ortega J, et al. Among authors: guinovart jj. EMBO Mol Med. 2011 Nov;3(11):667-81. doi: 10.1002/emmm.201100174. Epub 2011 Aug 29. EMBO Mol Med. 2011. PMID: 21882344 Free PMC article.
Muscle glycogen synthase isoform is responsible for testicular glycogen synthesis: glycogen overproduction induces apoptosis in male germ cells.
Villarroel-Espíndola F, Maldonado R, Mancilla H, vander Stelt K, Acuña AI, Covarrubias A, López C, Angulo C, Castro MA, Slebe JC, Durán J, García-Rocha M, Guinovart JJ, Concha II. Villarroel-Espíndola F, et al. Among authors: guinovart jj. J Cell Biochem. 2013 Jul;114(7):1653-64. doi: 10.1002/jcb.24507. J Cell Biochem. 2013. PMID: 23386391
Neurons have an active glycogen metabolism that contributes to tolerance to hypoxia.
Saez I, Duran J, Sinadinos C, Beltran A, Yanes O, Tevy MF, Martínez-Pons C, Milán M, Guinovart JJ. Saez I, et al. Among authors: guinovart jj. J Cereb Blood Flow Metab. 2014 Jun;34(6):945-55. doi: 10.1038/jcbfm.2014.33. Epub 2014 Feb 26. J Cereb Blood Flow Metab. 2014. PMID: 24569689 Free PMC article.
205 results