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Boiling down the cysteine-stabilized LTP fold - loss of structural and immunological integrity of allergenic Art v 3 and Pru p 3 as a consequence of irreversible lanthionine formation.
Wildner S, Griessner I, Stemeseder T, Regl C, Soh WT, Stock LG, Völker T, Alessandri C, Mari A, Huber CG, Stutz H, Brandstetter H, Gadermaier G. Wildner S, et al. Among authors: brandstetter h. Mol Immunol. 2019 Dec;116:140-150. doi: 10.1016/j.molimm.2019.10.012. Epub 2019 Oct 22. Mol Immunol. 2019. PMID: 31654938
Nitration of the birch pollen allergen Bet v 1.0101: efficiency and site-selectivity of liquid and gaseous nitrating agents.
Reinmuth-Selzle K, Ackaert C, Kampf CJ, Samonig M, Shiraiwa M, Kofler S, Yang H, Gadermaier G, Brandstetter H, Huber CG, Duschl A, Oostingh GJ, Pöschl U. Reinmuth-Selzle K, et al. Among authors: brandstetter h. J Proteome Res. 2014 Mar 7;13(3):1570-7. doi: 10.1021/pr401078h. Epub 2014 Feb 19. J Proteome Res. 2014. PMID: 24517313 Free PMC article.
Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.
Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, Weiss R. Machado Y, et al. Among authors: brandstetter h. J Allergy Clin Immunol. 2016 May;137(5):1525-34. doi: 10.1016/j.jaci.2015.09.026. Epub 2015 Nov 11. J Allergy Clin Immunol. 2016. PMID: 26559323 Free PMC article.
Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1-like protein family.
Stemeseder T, Freier R, Wildner S, Fuchs JE, Briza P, Lang R, Batanero E, Lidholm J, Liedl KR, Campo P, Hawranek T, Villalba M, Brandstetter H, Ferreira F, Gadermaier G. Stemeseder T, et al. Among authors: brandstetter h. J Allergy Clin Immunol. 2017 Jul;140(1):277-280. doi: 10.1016/j.jaci.2016.10.035. Epub 2016 Dec 10. J Allergy Clin Immunol. 2017. PMID: 27965108 Free PMC article. No abstract available.
133 results