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Two-carbon folate cycle of commensal Lactobacillus reuteri 6475 gives rise to immunomodulatory ethionine, a source for histone ethylation.
Röth D, Chiang AJ, Hu W, Gugiu GB, Morra CN, Versalovic J, Kalkum M. Röth D, et al. FASEB J. 2019 Mar;33(3):3536-3548. doi: 10.1096/fj.201801848R. Epub 2018 Nov 19. FASEB J. 2019. PMID: 30452879 Free PMC article.
Our findings suggest that the microbiome can expose the host to ethionine through a novel 2-carbon transporting variant of the folate cycle and modify human chromatin via ethylation.-Roth, D., Chiang, A. J., Hu, W., Gugiu, G. B., Morra, C. N., Versalovic, J., Kalkum …
Our findings suggest that the microbiome can expose the host to ethionine through a novel 2-carbon transporting variant of the folate cycle …
METTL3-Mediated m6A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL.
Wu Y, Jin M, Fernandez M, Hart KL, Liao A, Ge X, Fernandes SM, McDonald T, Chen Z, Röth D, Ghoda LY, Marcucci G, Kalkum M, Pillai RK, Danilov AV, Li JJ, Chen J, Brown JR, Rosen ST, Siddiqi T, Wang L. Wu Y, et al. Among authors: roth d. Blood Cancer Discov. 2023 May 1;4(3):228-245. doi: 10.1158/2643-3230.BCD-22-0156. Blood Cancer Discov. 2023. PMID: 37067905 Free PMC article.
E-cigarette-induced changes in cell stress and mitochondrial function.
Chitteti R, Zuniga-Hertz JP, Masso-Silva JA, Shin J, Niesman I, Bojanowski CM, Kumar AJ, Hepokoski M, Crotty Alexander LE, Patel HH, Roth DM. Chitteti R, et al. Among authors: roth dm. Free Radic Biol Med. 2025 Jan 3;228:329-338. doi: 10.1016/j.freeradbiomed.2025.01.004. Online ahead of print. Free Radic Biol Med. 2025. PMID: 39756490 Free article.
1,935 results