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Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft rejection.
Beier UH, Hartung EA, Concors S, Hernandez PT, Wang Z, Perry C, Baur JA, Denburg MR, Hancock WW, Gade TP, Levine MH. Beier UH, et al. Among authors: hernandez pt. Metabolomics. 2020 May 4;16(5):65. doi: 10.1007/s11306-020-01682-2. Metabolomics. 2020. PMID: 32367163 Free PMC article.
HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.
Aufhauser DD Jr, Hernandez P, Concors SJ, O'Brien C, Wang Z, Murken DR, Samanta A, Beier UH, Krumeich L, Bhatti TR, Wang Y, Ge G, Wang L, Cheraghlou S, Wagner FF, Holson EB, Kalin JH, Cole PA, Hancock WW, Levine MH. Aufhauser DD Jr, et al. Sci Rep. 2021 Apr 27;11(1):9018. doi: 10.1038/s41598-021-88242-3. Sci Rep. 2021. PMID: 33907245 Free PMC article.
Differential Effects of HDAC6 Inhibition Versus Knockout During Hepatic Ischemia-Reperfusion Injury Highlight Importance of HDAC6 C-terminal Zinc-finger Ubiquitin-binding Domain.
Concors SJ, Hernandez PT, O'Brien C, DePaolo J, Murken DR, Aufhauser DD, Wang Z, Xiong Y, Krumeich L, Ge G, Beier UH, Bhatti TR, Kozikowski AP, Avelar LAA, Kurz T, Hancock WW, Levine MH. Concors SJ, et al. Among authors: hernandez pt. Transplantation. 2024 Oct 1;108(10):2084-2092. doi: 10.1097/TP.0000000000005042. Epub 2024 Sep 24. Transplantation. 2024. PMID: 38685198
Diagnosis of Anastomotic Leak.
Hernandez PT, Paspulati RM, Shanmugan S. Hernandez PT, et al. Clin Colon Rectal Surg. 2021 Nov 23;34(6):391-399. doi: 10.1055/s-0041-1735270. eCollection 2021 Nov. Clin Colon Rectal Surg. 2021. PMID: 34853560 Free PMC article. Review.
Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages.
Alam Z, Devalaraja S, Li M, To TKJ, Folkert IW, Mitchell-Velasquez E, Dang MT, Young P, Wilbur CJ, Silverman MA, Li X, Chen YH, Hernandez PT, Bhattacharyya A, Bhattacharya M, Levine MH, Haldar M. Alam Z, et al. Among authors: hernandez pt. Cell Rep. 2020 Jun 30;31(13):107825. doi: 10.1016/j.celrep.2020.107825. Cell Rep. 2020. PMID: 32610126 Free PMC article.
13 results