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The antimicrobial peptide PFR induces necroptosis mediated by ER stress and elevated cytoplasmic calcium and mitochondrial ROS levels: cooperation with Ara-C to act against acute myeloid leukemia.
Lv Y, Shao G, Zhang Q, Wang X, Meng Y, Wang L, Huang F, Yang T, Jin Y, Fu C. Lv Y, et al. Among authors: wang x, wang l. Signal Transduct Target Ther. 2019 Oct 4;4:38. doi: 10.1038/s41392-019-0073-6. eCollection 2019. Signal Transduct Target Ther. 2019. PMID: 31637016 Free PMC article. No abstract available.
Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload.
Ge C, Huang H, Huang F, Yang T, Zhang T, Wu H, Zhou H, Chen Q, Shi Y, Sun Y, Liu L, Wang X, Pearson RB, Cao Y, Kang J, Fu C. Ge C, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19635-19645. doi: 10.1073/pnas.1908998116. Epub 2019 Sep 5. Proc Natl Acad Sci U S A. 2019. PMID: 31488714 Free PMC article.
A Novel Mechanism of Endoplasmic Reticulum Stress- and c-Myc-Degradation-Mediated Therapeutic Benefits of Antineurokinin-1 Receptor Drugs in Colorectal Cancer.
Shi Y, Wang X, Meng Y, Ma J, Zhang Q, Shao G, Wang L, Cheng X, Hong X, Wang Y, Yan Z, Cao Y, Kang J, Fu C. Shi Y, et al. Among authors: wang x, wang l, wang y. Adv Sci (Weinh). 2021 Nov;8(21):e2101936. doi: 10.1002/advs.202101936. Epub 2021 Oct 3. Adv Sci (Weinh). 2021. PMID: 34605226 Free PMC article.
Identification of ANXA1 as a Novel Upstream Negative Regulator of Notch1 Function in AML.
Shao G, Wang X, Zheng Y, Ma J, Wang L, Yan Z, Sun Z, Zhang S, Wu H, Lv Y, Huang H, Li J, Zhu T, Yang B, Wang N, Chen T, Guo X, Jin Y, Kang J, Wang H, Cao Y, Fu C. Shao G, et al. Among authors: wang x, wang h, wang l, wang n. Adv Sci (Weinh). 2024 Dec;11(48):e2409726. doi: 10.1002/advs.202409726. Epub 2024 Oct 24. Adv Sci (Weinh). 2024. PMID: 39447086 Free PMC article.
211,846 results
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