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A Somatostatin Receptor Subtype-3 (SST3) Peptide Agonist Shows Antitumor Effects in Experimental Models of Nonfunctioning Pituitary Tumors.
Vázquez-Borrego MC, Gupta V, Ibáñez-Costa A, Gahete MD, Venegas-Moreno E, Toledano-Delgado Á, Cano DA, Blanco-Acevedo C, Ortega-Salas R, Japón MA, Barrera-Martín A, Vasiljevic A, Hill J, Zhang S, Halem H, Solivera J, Raverot G, Gálvez MA, Soto-Moreno A, Paez-Pereda M, Culler MD, Castaño JP, Luque RM. Vázquez-Borrego MC, et al. Among authors: japon ma. Clin Cancer Res. 2020 Feb 15;26(4):957-969. doi: 10.1158/1078-0432.CCR-19-2154. Epub 2019 Oct 17. Clin Cancer Res. 2020. PMID: 31624102
A cellular and molecular basis for the selective desmopressin-induced ACTH release in Cushing disease patients: key role of AVPR1b receptor and potential therapeutic implications.
Luque RM, Ibáñez-Costa A, López-Sánchez LM, Jiménez-Reina L, Venegas-Moreno E, Gálvez MA, Villa-Osaba A, Madrazo-Atutxa AM, Japón MA, de la Riva A, Cano DA, Benito-López P, Soto-Moreno A, Gahete MD, Leal-Cerro A, Castaño JP. Luque RM, et al. Among authors: japon ma. J Clin Endocrinol Metab. 2013 Oct;98(10):4160-9. doi: 10.1210/jc.2013-1992. Epub 2013 Jul 24. J Clin Endocrinol Metab. 2013. PMID: 23884782
Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.
Diaz-Rodriguez E, Garcia-Rendueles AR, Ibáñez-Costa A, Gutierrez-Pascual E, Garcia-Lavandeira M, Leal A, Japon MA, Soto A, Venegas E, Tinahones FJ, Garcia-Arnes JA, Benito P, Angeles Galvez M, Jimenez-Reina L, Bernabeu I, Dieguez C, Luque RM, Castaño JP, Alvarez CV. Diaz-Rodriguez E, et al. Among authors: japon ma. Endocrinology. 2014 Nov;155(11):4329-40. doi: 10.1210/en.2014-1034. Epub 2014 Aug 19. Endocrinology. 2014. PMID: 25137025
In1-ghrelin splicing variant is overexpressed in pituitary adenomas and increases their aggressive features.
Ibáñez-Costa A, Gahete MD, Rivero-Cortés E, Rincón-Fernández D, Nelson R, Beltrán M, de la Riva A, Japón MA, Venegas-Moreno E, Gálvez MÁ, García-Arnés JA, Soto-Moreno A, Morgan J, Tsomaia N, Culler MD, Dieguez C, Castaño JP, Luque RM. Ibáñez-Costa A, et al. Among authors: japon ma. Sci Rep. 2015 Mar 4;5:8714. doi: 10.1038/srep08714. Sci Rep. 2015. PMID: 25737012 Free PMC article.
Octreotide and pasireotide (dis)similarly inhibit pituitary tumor cells in vitro.
Ibáñez-Costa A, Rivero-Cortés E, Vázquez-Borrego MC, Gahete MD, Jiménez-Reina L, Venegas-Moreno E, de la Riva A, Arráez MÁ, González-Molero I, Schmid HA, Maraver-Selfa S, Gavilán-Villarejo I, García-Arnés JA, Japón MA, Soto-Moreno A, Gálvez MA, Luque RM, Castaño JP. Ibáñez-Costa A, et al. Among authors: japon ma. J Endocrinol. 2016 Nov;231(2):135-145. doi: 10.1530/JOE-16-0332. Epub 2016 Sep 1. J Endocrinol. 2016. PMID: 27587848 Free article.
BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas.
Ibáñez-Costa A, López-Sánchez LM, Gahete MD, Rivero-Cortés E, Vázquez-Borrego MC, Gálvez MA, de la Riva A, Venegas-Moreno E, Jiménez-Reina L, Moreno-Carazo A, Tinahones FJ, Maraver-Selfa S, Japón MA, García-Arnés JA, Soto-Moreno A, Webb SM, Kineman RD, Culler MD, Castaño JP, Luque RM. Ibáñez-Costa A, et al. Among authors: japon ma. Sci Rep. 2017 Feb 9;7:42002. doi: 10.1038/srep42002. Sci Rep. 2017. PMID: 28181484 Free PMC article.
Association between dopamine and somatostatin receptor expression and pharmacological response to somatostatin analogues in acromegaly.
Venegas-Moreno E, Vazquez-Borrego MC, Dios E, Gros-Herguido N, Flores-Martinez A, Rivero-Cortés E, Madrazo-Atutxa A, Japón MA, Luque RM, Castaño JP, Cano DA, Soto-Moreno A. Venegas-Moreno E, et al. Among authors: japon ma. J Cell Mol Med. 2018 Mar;22(3):1640-1649. doi: 10.1111/jcmm.13440. Epub 2017 Dec 21. J Cell Mol Med. 2018. PMID: 29266696 Free PMC article.
E-cadherin expression is associated with somatostatin analogue response in acromegaly.
Venegas-Moreno E, Flores-Martinez A, Dios E, Vazquez-Borrego MC, Ibañez-Costa A, Madrazo-Atutxa A, Japón MA, Castaño JP, Luque RM, Cano DA, Soto-Moreno A. Venegas-Moreno E, et al. Among authors: japon ma. J Cell Mol Med. 2019 May;23(5):3088-3096. doi: 10.1111/jcmm.13851. Epub 2019 Mar 6. J Cell Mol Med. 2019. PMID: 30843342 Free PMC article.
Quantitative Analysis of Somatostatin and Dopamine Receptors Gene Expression Levels in Non-functioning Pituitary Tumors and Association with Clinical and Molecular Aggressiveness Features.
Flores-Martinez Á, Venegas-Moreno E, Dios E, Remón-Ruiz P, Gros-Herguido N, Vázquez-Borrego MC, Madrazo-Atutxa A, Japón MA, Kaen A, Cárdenas-Valdepeñas E, Roldán F, Castaño JP, Luque RM, Cano DA, Soto-Moreno A. Flores-Martinez Á, et al. Among authors: japon ma. J Clin Med. 2020 Sep 22;9(9):3052. doi: 10.3390/jcm9093052. J Clin Med. 2020. PMID: 32971845 Free PMC article.
Recommendations on the pathological report of pituitary tumors. A consensus of experts of the Spanish Society of Endocrinology and Nutrition and the Spanish Society of Pathology.
Picó A, Aranda-López I, Sesmilo G, Toldos-González Ó, Japón MA, Luque RM, Puig-Domingo M. Picó A, et al. Among authors: japon ma. Endocrinol Diabetes Nutr (Engl Ed). 2021 Mar;68(3):196-207. doi: 10.1016/j.endinu.2020.10.004. Epub 2021 Feb 3. Endocrinol Diabetes Nutr (Engl Ed). 2021. PMID: 33549511 Free article. English, Spanish.
67 results