Hegedűs L - Search Results

1

The Antitumor Effect of Lipophilic Bisphosphonate BPH1222 in Melanoma Models: The Role of the PI3K/Akt Pathway and the Small G Protein Rheb.

Rittler D, Baranyi M, Molnár E, Garay T, Jalsovszky I, Varga IK, Hegedűs L, Aigner C, Tóvári J, Tímár J, Hegedűs B. Rittler D, et al. Among authors: hegedus l, hegedus b. Int J Mol Sci. 2019 Oct 3;20(19):4917. doi: 10.3390/ijms20194917. Int J Mol Sci. 2019. PMID: 31623406 Free PMC article.

2

The plasma membrane Ca²⁺ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells.

Hegedũs L, Garay T, Molnár E, Varga K, Bilecz Á, Török S, Padányi R, Pászty K, Wolf M, Grusch M, Kállay E, Döme B, Berger W, Hegedũs B, Enyedi A. Hegedũs L, et al. Among authors: hegedus b. Int J Cancer. 2017 Jun 15;140(12):2758-2770. doi: 10.1002/ijc.30503. Epub 2016 Nov 17. Int J Cancer. 2017. PMID: 27813079

3

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca²⁺ Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK.

Hegedüs L, Padányi R, Molnár J, Pászty K, Varga K, Kenessey I, Sárközy E, Wolf M, Grusch M, Hegyi Z, Homolya L, Aigner C, Garay T, Hegedüs B, Tímár J, Kállay E, Enyedi Á. Hegedüs L, et al. Among authors: hegedus b. Front Oncol. 2017 May 24;7:95. doi: 10.3389/fonc.2017.00095. eCollection 2017. Front Oncol. 2017. PMID: 28596940 Free PMC article.

4

Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells.

Varga K, Hollósi A, Pászty K, Hegedűs L, Szakács G, Tímár J, Papp B, Enyedi Á, Padányi R. Varga K, et al. Among authors: hegedus l. BMC Cancer. 2018 Oct 23;18(1):1029. doi: 10.1186/s12885-018-4945-x. BMC Cancer. 2018. PMID: 30352569 Free PMC article.

5

Next Generation Lipophilic Bisphosphonate Shows Antitumor Effect in Colorectal Cancer In Vitro and In Vivo.

Baranyi M, Rittler D, Molnár E, Shirasawa S, Jalsovszky I, Varga IK, Hegedűs L, Németh A, Dank M, Aigner C, Tóvári J, Tímár J, Hegedűs B, Garay T. Baranyi M, et al. Among authors: hegedus l, hegedus b. Pathol Oncol Res. 2020 Jul;26(3):1957-1969. doi: 10.1007/s12253-019-00789-9. Epub 2020 Jan 4. Pathol Oncol Res. 2020. PMID: 31902117 Free article.

6

HDAC inhibition synergizes with ALK inhibitors to overcome resistance in a novel ALK mutated lung adenocarcinoma model.

Stockhammer P, Ho CSL, Hegedus L, Lotz G, Molnár E, Bankfalvi A, Herold T, Kalbourtzis S, Ploenes T, Eberhardt WEE, Schuler M, Aigner C, Schramm A, Hegedus B. Stockhammer P, et al. Among authors: hegedus l, hegedus b. Lung Cancer. 2020 Jun;144:20-29. doi: 10.1016/j.lungcan.2020.04.002. Epub 2020 Apr 18. Lung Cancer. 2020. PMID: 32353632

7

P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b.

Naffa R, Vogel L, Hegedűs L, Pászty K, Tóth S, Kelemen K, Singh N, Reményi A, Kállay E, Cserepes M, Tóvári J, Grusch M, Enyedi Á. Naffa R, et al. Among authors: hegedus l. Cells. 2020 May 13;9(5):1209. doi: 10.3390/cells9051209. Cells. 2020. PMID: 32414111 Free PMC article.

8

HDAC Inhibition Induces PD-L1 Expression in a Novel Anaplastic Thyroid Cancer Cell Line.

Hegedűs L, Rittler D, Garay T, Stockhammer P, Kovács I, Döme B, Theurer S, Hager T, Herold T, Kalbourtzis S, Bankfalvi A, Schmid KW, Führer D, Aigner C, Hegedűs B. Hegedűs L, et al. Among authors: hegedus b. Pathol Oncol Res. 2020 Oct;26(4):2523-2535. doi: 10.1007/s12253-020-00834-y. Epub 2020 Jun 26. Pathol Oncol Res. 2020. PMID: 32591993 Free PMC article.

9

Horizontal Combination of MEK and PI3K/mTOR Inhibition in BRAF Mutant Tumor Cells with or without Concomitant PI3K Pathway Mutations.

Rittler D, Molnár E, Baranyi M, Garay T, Hegedűs L, Aigner C, Tóvári J, Tímár J, Hegedűs B. Rittler D, et al. Among authors: hegedus l, hegedus b. Int J Mol Sci. 2020 Oct 16;21(20):7649. doi: 10.3390/ijms21207649. Int J Mol Sci. 2020. PMID: 33081092 Free PMC article.

10

Allosteric and ATP-Competitive MEK-Inhibition in a Novel Spitzoid Melanoma Model with a RAF- and Phosphorylation-Independent Mutation.

Hegedüs L, Okumus Ö, Livingstone E, Baranyi M, Kovács I, Döme B, Tóvári J, Bánkfalvi Á, Schadendorf D, Aigner C, Hegedüs B. Hegedüs L, et al. Among authors: hegedus b. Cancers (Basel). 2021 Feb 16;13(4):829. doi: 10.3390/cancers13040829. Cancers (Basel). 2021. PMID: 33669371 Free PMC article.

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