Rischert N - Search Results

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Brain-penetrant PQR620 mTOR and PQR530 PI3K/mTOR inhibitor reduce huntingtin levels in cell models of HD.

Singer E, Walter C, Fabbro D, Rageot D, Beaufils F, Wymann MP, Rischert N, Riess O, Hillmann P, Nguyen HP. Singer E, et al. Among authors: rischert n. Neuropharmacology. 2020 Jan 1;162:107812. doi: 10.1016/j.neuropharm.2019.107812. Epub 2019 Oct 14. Neuropharmacology. 2020. PMID: 31622602

Reduced cell size, chromosomal aberration and altered proliferation rates are characteristics and confounding factors in the STHdh cell model of Huntington disease.

Singer E, Walter C, Weber JJ, Krahl AC, Mau-Holzmann UA, Rischert N, Riess O, Clemensson LE, Nguyen HP. Singer E, et al. Among authors: rischert n. Sci Rep. 2017 Dec 4;7(1):16880. doi: 10.1038/s41598-017-17275-4. Sci Rep. 2017. PMID: 29203806 Free PMC article.

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