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Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.
Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T. Katholnig K, et al. Among authors: spittler a. JCI Insight. 2019 Oct 17;4(20):e124164. doi: 10.1172/jci.insight.124164. JCI Insight. 2019. PMID: 31619583 Free PMC article.
Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1.
Edlinger L, Berger-Becvar A, Menzl I, Hoermann G, Greiner G, Grundschober E, Bago-Horvath Z, Al-Zoughbi W, Hoefler G, Brostjan C, Gille L, Moriggl R, Spittler A, Sexl V, Hoelbl-Kovacic A. Edlinger L, et al. Among authors: spittler a. Br J Haematol. 2017 Oct;179(2):229-241. doi: 10.1111/bjh.14833. Epub 2017 Jul 14. Br J Haematol. 2017. PMID: 28707321 Free PMC article.
172 results