Cassell RJ - Search Results

1

Selection of DNA-Encoded Libraries to Protein Targets within and on Living Cells.

Cai B, Kim D, Akhand S, Sun Y, Cassell RJ, Alpsoy A, Dykhuizen EC, Van Rijn RM, Wendt MK, Krusemark CJ. Cai B, et al. Among authors: cassell rj. J Am Chem Soc. 2019 Oct 30;141(43):17057-17061. doi: 10.1021/jacs.9b08085. Epub 2019 Oct 22. J Am Chem Soc. 2019. PMID: 31613623 Free PMC article.

2

Arrestin recruitment and signaling by G protein-coupled receptor heteromers.

Mores KL, Cassell RJ, van Rijn RM. Mores KL, et al. Among authors: cassell rj. Neuropharmacology. 2019 Jul 1;152:15-21. doi: 10.1016/j.neuropharm.2018.11.010. Epub 2018 Nov 9. Neuropharmacology. 2019. PMID: 30419245 Free PMC article. Review.

3

Rubiscolins are naturally occurring G protein-biased delta opioid receptor peptides.

Cassell RJ, Mores KL, Zerfas BL, Mahmoud AH, Lill MA, Trader DJ, van Rijn RM. Cassell RJ, et al. Eur Neuropsychopharmacol. 2019 Mar;29(3):450-456. doi: 10.1016/j.euroneuro.2018.12.013. Epub 2018 Dec 24. Eur Neuropsychopharmacol. 2019. PMID: 30591345 Free PMC article.

4

A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists.

Mores KL, Cummins BR, Cassell RJ, van Rijn RM. Mores KL, et al. Among authors: cassell rj. Front Pharmacol. 2019 Apr 17;10:407. doi: 10.3389/fphar.2019.00407. eCollection 2019. Front Pharmacol. 2019. PMID: 31057409 Free PMC article. Review.

5

G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder.

Gutridge AM, Robins MT, Cassell RJ, Uprety R, Mores KL, Ko MJ, Pasternak GW, Majumdar S, van Rijn RM. Gutridge AM, et al. Among authors: cassell rj. Br J Pharmacol. 2020 Apr;177(7):1497-1513. doi: 10.1111/bph.14913. Epub 2020 Jan 24. Br J Pharmacol. 2020. PMID: 31705528 Free PMC article.

6

The Meta-Position of Phe⁴ in Leu-Enkephalin Regulates Potency, Selectivity, Functional Activity, and Signaling Bias at the Delta and Mu Opioid Receptors.

Cassell RJ, Sharma KK, Su H, Cummins BR, Cui H, Mores KL, Blaine AT, Altman RA, van Rijn RM. Cassell RJ, et al. Molecules. 2019 Dec 12;24(24):4542. doi: 10.3390/molecules24244542. Molecules. 2019. PMID: 31842282 Free PMC article.

7

Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder.

Gutridge AM, Chakraborty S, Varga BR, Rhoda ES, French AR, Blaine AT, Royer QH, Cui H, Yuan J, Cassell RJ, Szabó M, Majumdar S, van Rijn RM. Gutridge AM, et al. Among authors: cassell rj. Front Pharmacol. 2021 Nov 3;12:764885. doi: 10.3389/fphar.2021.764885. eCollection 2021. Front Pharmacol. 2021. PMID: 34803709 Free PMC article.

8

Modulating β-arrestin 2 recruitment at the δ- and μ-opioid receptors using peptidomimetic ligands.

Sharma KK, Cassell RJ, Meqbil YJ, Su H, Blaine AT, Cummins BR, Mores KL, Johnson DK, van Rijn RM, Altman RA. Sharma KK, et al. Among authors: cassell rj. RSC Med Chem. 2021 Aug 16;12(11):1958-1967. doi: 10.1039/d1md00025j. eCollection 2021 Nov 17. RSC Med Chem. 2021. PMID: 34825191 Free PMC article.

9

Identification of a Novel Delta Opioid Receptor Agonist Chemotype with Potential Negative Allosteric Modulator Capabilities.

Meqbil YJ, Su H, Cassell RJ, Mores KL, Gutridge AM, Cummins BR, Chen L, van Rijn RM. Meqbil YJ, et al. Among authors: cassell rj. Molecules. 2021 Nov 29;26(23):7236. doi: 10.3390/molecules26237236. Molecules. 2021. PMID: 34885825 Free PMC article.

10

Identification of 1,3,8-Triazaspiro[4.5]Decane-2,4-Dione Derivatives as a Novel δ Opioid Receptor-Selective Agonist Chemotype.

Meqbil YJ, Aguilar J, Blaine AT, Chen L, Cassell RJ, Pradhan AA, van Rijn RM. Meqbil YJ, et al. Among authors: cassell rj. J Pharmacol Exp Ther. 2024 May 21;389(3):301-309. doi: 10.1124/jpet.123.001735. J Pharmacol Exp Ther. 2024. PMID: 38621994

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