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Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function.
Bian Z, Wang Q, Zhou X, Tan T, Park KH, Kramer HF, McDougal A, Laping NJ, Kumar S, Adesanya TMA, Sermersheim M, Yi F, Wang X, Wu J, Gumpper K, Jiang Q, He D, Lin PH, Li H, Guan F, Zhou J, Kohr MJ, Zeng C, Zhu H, Ma J. Bian Z, et al. Among authors: ma j. Nat Commun. 2019 Oct 11;10(1):4659. doi: 10.1038/s41467-019-12483-0. Nat Commun. 2019. PMID: 31604915 Free PMC article.
MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling.
Yi JS, Park JS, Ham YM, Nguyen N, Lee NR, Hong J, Kim BW, Lee H, Lee CS, Jeong BC, Song HK, Cho H, Kim YK, Lee JS, Park KS, Shin H, Choi I, Lee SH, Park WJ, Park SY, Choi CS, Lin P, Karunasiri M, Tan T, Duann P, Zhu H, Ma J, Ko YG. Yi JS, et al. Among authors: ma j. Nat Commun. 2013;4:2354. doi: 10.1038/ncomms3354. Nat Commun. 2013. PMID: 23965929 Free PMC article.
Treatment of acute lung injury by targeting MG53-mediated cell membrane repair.
Jia Y, Chen K, Lin P, Lieber G, Nishi M, Yan R, Wang Z, Yao Y, Li Y, Whitson BA, Duann P, Li H, Zhou X, Zhu H, Takeshima H, Hunter JC, McLeod RL, Weisleder N, Zeng C, Ma J. Jia Y, et al. Among authors: ma j. Nat Commun. 2014 Jul 18;5:4387. doi: 10.1038/ncomms5387. Nat Commun. 2014. PMID: 25034454 Free PMC article.
MG53 Does Not Manifest the Development of Diabetes in db/db Mice.
Wang Q, Bian Z, Jiang Q, Wang X, Zhou X, Park KH, Hsueh W, Whitson BA, Haggard E, Li H, Chen K, Cai C, Tan T, Zhu H, Ma J. Wang Q, et al. Among authors: ma j. Diabetes. 2020 May;69(5):1052-1064. doi: 10.2337/db19-0807. Epub 2020 Mar 5. Diabetes. 2020. PMID: 32139593 Free PMC article.
MG53 promotes corneal wound healing and mitigates fibrotic remodeling in rodents.
Chandler HL, Tan T, Yang C, Gemensky-Metzler AJ, Wehrman RF, Jiang Q, Peterson CMW, Geng B, Zhou X, Wang Q, Kaili D, Adesanya TMA, Yi F, Zhu H, Ma J. Chandler HL, et al. Among authors: ma j. Commun Biol. 2019 Feb 20;2:71. doi: 10.1038/s42003-019-0316-7. eCollection 2019. Commun Biol. 2019. PMID: 30793049 Free PMC article.
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