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109 results

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Page 1
Application of the adverse outcome pathway framework to genotoxic modes of action.
Sasaki JC, Allemang A, Bryce SM, Custer L, Dearfield KL, Dietz Y, Elhajouji A, Escobar PA, Fornace AJ Jr, Froetschl R, Galloway S, Hemmann U, Hendriks G, Li HH, Luijten M, Ouedraogo G, Peel L, Pfuhler S, Roberts DJ, Thybaud V, van Benthem J, Yauk CL, Schuler M. Sasaki JC, et al. Among authors: van benthem j. Environ Mol Mutagen. 2020 Jan;61(1):114-134. doi: 10.1002/em.22339. Epub 2019 Oct 31. Environ Mol Mutagen. 2020. PMID: 31603995
Follow-up actions from positive results of in vitro genetic toxicity testing.
Dearfield KL, Thybaud V, Cimino MC, Custer L, Czich A, Harvey JS, Hester S, Kim JH, Kirkland D, Levy DD, Lorge E, Moore MM, Ouédraogo-Arras G, Schuler M, Suter W, Sweder K, Tarlo K, van Benthem J, van Goethem F, Witt KL. Dearfield KL, et al. Among authors: van goethem f, van benthem j. Environ Mol Mutagen. 2011 Apr;52(3):177-204. doi: 10.1002/em.20617. Epub 2010 Oct 20. Environ Mol Mutagen. 2011. PMID: 20963811 Free article. Review.
Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations.
Dearfield KL, Gollapudi BB, Bemis JC, Benz RD, Douglas GR, Elespuru RK, Johnson GE, Kirkland DJ, LeBaron MJ, Li AP, Marchetti F, Pottenger LH, Rorije E, Tanir JY, Thybaud V, van Benthem J, Yauk CL, Zeiger E, Luijten M. Dearfield KL, et al. Among authors: van benthem j. Environ Mol Mutagen. 2017 Jun;58(5):264-283. doi: 10.1002/em.22045. Epub 2016 Sep 21. Environ Mol Mutagen. 2017. PMID: 27650663 Review.
Utility of a next generation framework for assessment of genomic damage: A case study using the industrial chemical benzene.
Luijten M, Ball NS, Dearfield KL, Gollapudi BB, Johnson GE, Madia F, Peel L, Pfuhler S, Settivari RS, Ter Burg W, White PA, van Benthem J. Luijten M, et al. Among authors: van benthem j. Environ Mol Mutagen. 2020 Jan;61(1):94-113. doi: 10.1002/em.22346. Epub 2019 Nov 27. Environ Mol Mutagen. 2020. PMID: 31709603 Free PMC article. Review.
Quantitative approaches for assessing dose-response relationships in genetic toxicology studies.
Gollapudi BB, Johnson GE, Hernandez LG, Pottenger LH, Dearfield KL, Jeffrey AM, Julien E, Kim JH, Lovell DP, Macgregor JT, Moore MM, van Benthem J, White PA, Zeiger E, Thybaud V. Gollapudi BB, et al. Among authors: van benthem j. Environ Mol Mutagen. 2013 Jan;54(1):8-18. doi: 10.1002/em.21727. Epub 2012 Sep 18. Environ Mol Mutagen. 2013. PMID: 22987251
New and emerging technologies for genetic toxicity testing.
Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A Jr, Honma M, Naven RT, Rusling JF, Schiestl RH, Walmsley RM, Yamamura E, van Benthem J, Kim JH. Lynch AM, et al. Among authors: van benthem j. Environ Mol Mutagen. 2011 Apr;52(3):205-23. doi: 10.1002/em.20614. Epub 2010 Aug 25. Environ Mol Mutagen. 2011. PMID: 20740635 Review.
The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development.
Yauk CL, Bishop J, Dearfield KL, Douglas GR, Hales BF, Luijten M, O'Brien JM, Robaire B, Sram R, van Benthem J, Wade MG, White PA, Marchetti F. Yauk CL, et al. Among authors: van benthem j. Environ Mol Mutagen. 2013 Mar;54(2):79-81. doi: 10.1002/em.21757. Epub 2013 Jan 28. Environ Mol Mutagen. 2013. PMID: 23355186 No abstract available.
Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Reports of individual databases presented at an EURL ECVAM Workshop.
Kirkland D, Zeiger E, Madia F, Gooderham N, Kasper P, Lynch A, Morita T, Ouedraogo G, Parra Morte JM, Pfuhler S, Rogiers V, Schulz M, Thybaud V, van Benthem J, Vanparys P, Worth A, Corvi R. Kirkland D, et al. Among authors: van benthem j. Mutat Res Genet Toxicol Environ Mutagen. 2014 Dec;775-776:55-68. doi: 10.1016/j.mrgentox.2014.10.005. Epub 2014 Oct 23. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 25435356 Free article.
109 results