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Structural basis for the docking of mTORC1 on the lysosomal surface.
Rogala KB, Gu X, Kedir JF, Abu-Remaileh M, Bianchi LF, Bottino AMS, Dueholm R, Niehaus A, Overwijn D, Fils AP, Zhou SX, Leary D, Laqtom NN, Brignole EJ, Sabatini DM. Rogala KB, et al. Among authors: kedir jf. Science. 2019 Oct 25;366(6464):468-475. doi: 10.1126/science.aay0166. Epub 2019 Oct 10. Science. 2019. PMID: 31601708 Free PMC article.
Amino acids and KLHL22 do not activate mTORC1 via DEPDC5 degradation.
Valenstein ML, Lalgudi PV, Kedir JF, Condon KJ, Platzek A, Freund DG, Taylor MS, Xu Y, Chivukula RR, Sabatini DM. Valenstein ML, et al. Among authors: kedir jf. Nature. 2025 Jan;637(8045):E11-E14. doi: 10.1038/s41586-024-07974-0. Epub 2025 Jan 8. Nature. 2025. PMID: 39780017 No abstract available.