Groth T - Search Results

1

Doxycycline-Dependent Self-Inactivation of CRISPR-Cas9 to Temporally Regulate On- and Off-Target Editing.

Kelkar A, Zhu Y, Groth T, Stolfa G, Stablewski AB, Singhi N, Nemeth M, Neelamegham S. Kelkar A, et al. Among authors: groth t. Mol Ther. 2020 Jan 8;28(1):29-41. doi: 10.1016/j.ymthe.2019.09.006. Epub 2019 Sep 12. Mol Ther. 2020. PMID: 31601489 Free PMC article.

2

A GlycoGene CRISPR-Cas9 lentiviral library to study lectin binding and human glycan biosynthesis pathways.

Zhu Y, Groth T, Kelkar A, Zhou Y, Neelamegham S. Zhu Y, et al. Among authors: groth t. Glycobiology. 2021 Apr 1;31(3):173-180. doi: 10.1093/glycob/cwaa074. Glycobiology. 2021. PMID: 32776087 Free PMC article.

3

A systems-based framework to computationally describe putative transcription factors and signaling pathways regulating glycan biosynthesis.

Groth T, Gunawan R, Neelamegham S. Groth T, et al. Beilstein J Org Chem. 2021 Jul 22;17:1712-1724. doi: 10.3762/bjoc.17.119. eCollection 2021. Beilstein J Org Chem. 2021. PMID: 34367349 Free PMC article.

4

Forward Genetic Screens of Human Glycosylation Pathways Using the GlycoGene CRISPR Library.

Kelkar A, Groth T, Neelamegham S. Kelkar A, et al. Among authors: groth t. Curr Protoc. 2022 Apr;2(4):e402. doi: 10.1002/cpz1.402. Curr Protoc. 2022. PMID: 35427438 Free PMC article.

5

GlycoEnzOnto: a GlycoEnzyme pathway and molecular function ontology.

Groth T, Diehl AD, Gunawan R, Neelamegham S. Groth T, et al. Bioinformatics. 2022 Dec 13;38(24):5413-5420. doi: 10.1093/bioinformatics/btac704. Bioinformatics. 2022. PMID: 36282863 Free PMC article.

6

Cadherin-11 increases tumor cell proliferation and metastatic potential via Wnt pathway activation.

Liu Y, Lei P, Samuel RZ, Kashyap AM, Groth T, Bshara W, Neelamegham S, Andreadis ST. Liu Y, et al. Among authors: groth t. Mol Oncol. 2023 Oct;17(10):2056-2073. doi: 10.1002/1878-0261.13507. Epub 2023 Sep 8. Mol Oncol. 2023. PMID: 37558205 Free PMC article.

7

FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells.

Warren I, Moeller MM, Guiggey D, Chiang A, Maloy M, Ogoke O, Groth T, Mon T, Meamardoost S, Liu X, Thompson S, Szeglowski A, Thompson R, Chen P, Paulmurugan R, Yarmush ML, Kidambi S, Parashurama N. Warren I, et al. Among authors: groth t. FASEB J. 2023 Jan;37(1):e22652. doi: 10.1096/fj.202101506RRR. FASEB J. 2023. PMID: 36515690

8

Whole-genome sequence of an evolved Clostridium pasteurianum strain reveals Spo0A deficiency responsible for increased butanol production and superior growth.

Sandoval NR, Venkataramanan KP, Groth TS, Papoutsakis ET. Sandoval NR, et al. Among authors: groth ts. Biotechnol Biofuels. 2015 Dec 24;8:227. doi: 10.1186/s13068-015-0408-7. eCollection 2015. Biotechnol Biofuels. 2015. PMID: 26705421 Free PMC article.

9

Inert splint-driven oligonucleotide assembly.

Mishin AA, Groth T, Green RE, Troll CJ. Mishin AA, et al. Among authors: groth t. Synth Biol (Oxf). 2024 Dec 13;9(1):ysae019. doi: 10.1093/synbio/ysae019. eCollection 2024. Synth Biol (Oxf). 2024. PMID: 39734808 Free PMC article.

10

3D-printed microstructured alginate scaffolds for neural tissue engineering.

Li J, Hietel B, Brunk MGK, Reimers A, Willems C, Groth T, Cynis H, Adelung R, Schütt F, Sacher WD, Poon JKS. Li J, et al. Among authors: groth t. Trends Biotechnol. 2024 Dec 9:S0167-7799(24)00304-4. doi: 10.1016/j.tibtech.2024.10.013. Online ahead of print. Trends Biotechnol. 2024. PMID: 39658448 Free article.

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