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Structure of the mitochondrial import gate reveals distinct preprotein paths.
Araiso Y, Tsutsumi A, Qiu J, Imai K, Shiota T, Song J, Lindau C, Wenz LS, Sakaue H, Yunoki K, Kawano S, Suzuki J, Wischnewski M, Schütze C, Ariyama H, Ando T, Becker T, Lithgow T, Wiedemann N, Pfanner N, Kikkawa M, Endo T. Araiso Y, et al. Among authors: kikkawa m. Nature. 2019 Nov;575(7782):395-401. doi: 10.1038/s41586-019-1680-7. Epub 2019 Oct 10. Nature. 2019. PMID: 31600774
Switch-based mechanism of kinesin motors.
Kikkawa M, Sablin EP, Okada Y, Yajima H, Fletterick RJ, Hirokawa N. Kikkawa M, et al. Nature. 2001 May 24;411(6836):439-45. doi: 10.1038/35078000. Nature. 2001. PMID: 11373668
Cryo-EM structures of the human volume-regulated anion channel LRRC8.
Kasuya G, Nakane T, Yokoyama T, Jia Y, Inoue M, Watanabe K, Nakamura R, Nishizawa T, Kusakizako T, Tsutsumi A, Yanagisawa H, Dohmae N, Hattori M, Ichijo H, Yan Z, Kikkawa M, Shirouzu M, Ishitani R, Nureki O. Kasuya G, et al. Among authors: kikkawa m. Nat Struct Mol Biol. 2018 Sep;25(9):797-804. doi: 10.1038/s41594-018-0109-6. Epub 2018 Aug 20. Nat Struct Mol Biol. 2018. PMID: 30127360
Structural analysis reveals TLR7 dynamics underlying antagonism.
Tojo S, Zhang Z, Matsui H, Tahara M, Ikeguchi M, Kochi M, Kamada M, Shigematsu H, Tsutsumi A, Adachi N, Shibata T, Yamamoto M, Kikkawa M, Senda T, Isobe Y, Ohto U, Shimizu T. Tojo S, et al. Among authors: kikkawa m. Nat Commun. 2020 Oct 15;11(1):5204. doi: 10.1038/s41467-020-19025-z. Nat Commun. 2020. PMID: 33060576 Free PMC article.
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion.
Matoba K, Kotani T, Tsutsumi A, Tsuji T, Mori T, Noshiro D, Sugita Y, Nomura N, Iwata S, Ohsumi Y, Fujimoto T, Nakatogawa H, Kikkawa M, Noda NN. Matoba K, et al. Among authors: kikkawa m. Nat Struct Mol Biol. 2020 Dec;27(12):1185-1193. doi: 10.1038/s41594-020-00518-w. Epub 2020 Oct 26. Nat Struct Mol Biol. 2020. PMID: 33106658
160 results