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A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation.
Bernstock JD, Lee YJ, Peruzzotti-Jametti L, Southall N, Johnson KR, Maric D, Volpe G, Kouznetsova J, Zheng W, Pluchino S, Hallenbeck JM. Bernstock JD, et al. J Cereb Blood Flow Metab. 2016 Feb;36(2):426-41. doi: 10.1177/0271678X15609939. Epub 2015 Oct 23. J Cereb Blood Flow Metab. 2016. PMID: 26661196 Free PMC article.
SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke.
Bernstock JD, Peruzzotti-Jametti L, Leonardi T, Vicario N, Ye D, Lee YJ, Maric D, Johnson KR, Mou Y, Van Den Bosch A, Winterbone M, Friedman GK, Franklin RJM, Hallenbeck JM, Pluchino S. Bernstock JD, et al. EBioMedicine. 2019 Apr;42:214-224. doi: 10.1016/j.ebiom.2019.03.035. Epub 2019 Mar 21. EBioMedicine. 2019. PMID: 30905846 Free PMC article.
A novel in situ multiplex immunofluorescence panel for the assessment of tumor immunopathology and response to virotherapy in pediatric glioblastoma reveals a role for checkpoint protein inhibition.
Bernstock JD, Vicario N, Rong L, Valdes PA, Choi BD, Chen JA, DiToro D, Osorio DS, Kachurak K, Gessler F, Johnston JM Jr, Atkinson TP, Whitley RJ, Bag AK, Gillespie GY, Markert JM, Maric D, Friedman GK. Bernstock JD, et al. Oncoimmunology. 2019 Oct 21;8(12):e1678921. doi: 10.1080/2162402X.2019.1678921. eCollection 2019. Oncoimmunology. 2019. PMID: 31741780 Free PMC article.
Small ubiquitin-like modifier 2 (SUMO2) is critical for memory processes in mice.
Yu S, Galeffi F, Rodriguiz RM, Wang Z, Shen Y, Lyu J, Li R, Bernstock JD, Johnson KR, Liu S, Sheng H, Turner DA, Wetsel WC, Paschen W, Yang W. Yu S, et al. Among authors: bernstock jd. FASEB J. 2020 Nov;34(11):14750-14767. doi: 10.1096/fj.202000850RR. Epub 2020 Sep 10. FASEB J. 2020. PMID: 32910521 Free PMC article.
Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats.
Zhao J, Mou Y, Bernstock JD, Klimanis D, Wang S, Spatz M, Maric D, Johnson K, Klinman DM, Li X, Li X, Hallenbeck JM. Zhao J, et al. Among authors: bernstock jd. PLoS One. 2015 Oct 16;10(10):e0140772. doi: 10.1371/journal.pone.0140772. eCollection 2015. PLoS One. 2015. PMID: 26473731 Free PMC article.
Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas.
Friedman GK, Johnston JM, Bag AK, Bernstock JD, Li R, Aban I, Kachurak K, Nan L, Kang KD, Totsch S, Schlappi C, Martin AM, Pastakia D, McNall-Knapp R, Farouk Sait S, Khakoo Y, Karajannis MA, Woodling K, Palmer JD, Osorio DS, Leonard J, Abdelbaki MS, Madan-Swain A, Atkinson TP, Whitley RJ, Fiveash JB, Markert JM, Gillespie GY. Friedman GK, et al. Among authors: bernstock jd. N Engl J Med. 2021 Apr 29;384(17):1613-1622. doi: 10.1056/NEJMoa2024947. Epub 2021 Apr 10. N Engl J Med. 2021. PMID: 33838625 Free PMC article.
196 results