Joseph RE - Search Results

1

Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases.

Amatya N, Wales TE, Kwon A, Yeung W, Joseph RE, Fulton DB, Kannan N, Engen JR, Andreotti AH. Amatya N, et al. Among authors: joseph re. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21539-21544. doi: 10.1073/pnas.1907566116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591208 Free PMC article.

2

The linker between SH2 and kinase domains positively regulates catalysis of the Tec family kinases.

Joseph RE, Min L, Andreotti AH. Joseph RE, et al. Biochemistry. 2007 May 8;46(18):5455-62. doi: 10.1021/bi602512e. Epub 2007 Apr 11. Biochemistry. 2007. PMID: 17425330 Free article.

3

A remote substrate docking mechanism for the tec family tyrosine kinases.

Joseph RE, Min L, Xu R, Musselman ED, Andreotti AH. Joseph RE, et al. Biochemistry. 2007 May 8;46(18):5595-603. doi: 10.1021/bi700127c. Epub 2007 Apr 17. Biochemistry. 2007. PMID: 17439160 Free article.

4

Mechanism and functional significance of Itk autophosphorylation.

Joseph RE, Fulton DB, Andreotti AH. Joseph RE, et al. J Mol Biol. 2007 Nov 9;373(5):1281-92. doi: 10.1016/j.jmb.2007.08.060. Epub 2007 Aug 31. J Mol Biol. 2007. PMID: 17897671 Free PMC article.

5

Bacterial expression and purification of interleukin-2 tyrosine kinase: single step separation of the chaperonin impurity.

Joseph RE, Andreotti AH. Joseph RE, et al. Protein Expr Purif. 2008 Aug;60(2):194-7. doi: 10.1016/j.pep.2008.04.001. Epub 2008 Apr 11. Protein Expr Purif. 2008. PMID: 18495488 Free PMC article.

6

Conformational snapshots of Tec kinases during signaling.

Joseph RE, Andreotti AH. Joseph RE, et al. Immunol Rev. 2009 Mar;228(1):74-92. doi: 10.1111/j.1600-065X.2008.00740.x. Immunol Rev. 2009. PMID: 19290922 Free PMC article.

7

Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.

Severin A, Joseph RE, Boyken S, Fulton DB, Andreotti AH. Severin A, et al. Among authors: joseph re. J Mol Biol. 2009 Apr 3;387(3):726-43. doi: 10.1016/j.jmb.2009.02.012. Epub 2009 Feb 12. J Mol Biol. 2009. PMID: 19361414 Free PMC article.

8

SH2-dependent autophosphorylation within the Tec family kinase Itk.

Joseph RE, Severin A, Min L, Fulton DB, Andreotti AH. Joseph RE, et al. J Mol Biol. 2009 Aug 7;391(1):164-77. doi: 10.1016/j.jmb.2009.06.023. Epub 2009 Jun 11. J Mol Biol. 2009. PMID: 19523959 Free PMC article.

9

Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1.

Min L, Joseph RE, Fulton DB, Andreotti AH. Min L, et al. Among authors: joseph re. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21143-8. doi: 10.1073/pnas.0911309106. Epub 2009 Dec 1. Proc Natl Acad Sci U S A. 2009. PMID: 19955438 Free PMC article.

10

Disrupting the intermolecular self-association of Itk enhances T cell signaling.

Min L, Wu W, Joseph RE, Fulton DB, Berg L, Andreotti AH. Min L, et al. Among authors: joseph re. J Immunol. 2010 Apr 15;184(8):4228-35. doi: 10.4049/jimmunol.0901908. Epub 2010 Mar 17. J Immunol. 2010. PMID: 20237289 Free PMC article.

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