Fulton DB - Search Results

1

Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases.

Amatya N, Wales TE, Kwon A, Yeung W, Joseph RE, Fulton DB, Kannan N, Engen JR, Andreotti AH. Amatya N, et al. Among authors: fulton db. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21539-21544. doi: 10.1073/pnas.1907566116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591208 Free PMC article.

2

Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A.

Brazin KN, Mallis RJ, Fulton DB, Andreotti AH. Brazin KN, et al. Among authors: fulton db. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1899-904. doi: 10.1073/pnas.042529199. Epub 2002 Feb 5. Proc Natl Acad Sci U S A. 2002. PMID: 11830645 Free PMC article.

3

Mechanism and functional significance of Itk autophosphorylation.

Joseph RE, Fulton DB, Andreotti AH. Joseph RE, et al. Among authors: fulton db. J Mol Biol. 2007 Nov 9;373(5):1281-92. doi: 10.1016/j.jmb.2007.08.060. Epub 2007 Aug 31. J Mol Biol. 2007. PMID: 17897671 Free PMC article.

4

Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.

Severin A, Joseph RE, Boyken S, Fulton DB, Andreotti AH. Severin A, et al. Among authors: fulton db. J Mol Biol. 2009 Apr 3;387(3):726-43. doi: 10.1016/j.jmb.2009.02.012. Epub 2009 Feb 12. J Mol Biol. 2009. PMID: 19361414 Free PMC article.

5

SH2-dependent autophosphorylation within the Tec family kinase Itk.

Joseph RE, Severin A, Min L, Fulton DB, Andreotti AH. Joseph RE, et al. Among authors: fulton db. J Mol Biol. 2009 Aug 7;391(1):164-77. doi: 10.1016/j.jmb.2009.06.023. Epub 2009 Jun 11. J Mol Biol. 2009. PMID: 19523959 Free PMC article.

6

Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1.

Min L, Joseph RE, Fulton DB, Andreotti AH. Min L, et al. Among authors: fulton db. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21143-8. doi: 10.1073/pnas.0911309106. Epub 2009 Dec 1. Proc Natl Acad Sci U S A. 2009. PMID: 19955438 Free PMC article.

7

Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures.

Joseph RE, Ginder ND, Hoy JA, Nix JC, Fulton DB, Honzatko RB, Andreotti AH. Joseph RE, et al. Among authors: fulton db. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):145-53. doi: 10.1107/S1744309111049761. Epub 2012 Jan 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22297986 Free PMC article.

8

Rescue of the aggregation prone Itk Pleckstrin Homology domain by two mutations derived from the related kinases, Btk and Tec.

Boyken SE, Fulton DB, Andreotti AH. Boyken SE, et al. Among authors: fulton db. Protein Sci. 2012 Sep;21(9):1288-97. doi: 10.1002/pro.2114. Epub 2012 Jul 16. Protein Sci. 2012. PMID: 22761113 Free PMC article.

9

Substrate recognition of PLCγ1 via a specific docking surface on Itk.

Xie Q, Joseph RE, Fulton DB, Andreotti AH. Xie Q, et al. Among authors: fulton db. J Mol Biol. 2013 Feb 22;425(4):683-96. doi: 10.1016/j.jmb.2012.10.023. Epub 2012 Dec 3. J Mol Biol. 2013. PMID: 23219468 Free PMC article.

10

Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases.

Joseph RE, Kleino I, Wales TE, Xie Q, Fulton DB, Engen JR, Berg LJ, Andreotti AH. Joseph RE, et al. Among authors: fulton db. Sci Signal. 2013 Aug 27;6(290):ra76. doi: 10.1126/scisignal.2004298. Sci Signal. 2013. PMID: 23982207 Free PMC article.

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