Garcia-Luis J - Search Results

1

FACT mediates cohesin function on chromatin.

Garcia-Luis J, Lazar-Stefanita L, Gutierrez-Escribano P, Thierry A, Cournac A, García A, González S, Sánchez M, Jarmuz A, Montoya A, Dore M, Kramer H, Karimi MM, Antequera F, Koszul R, Aragon L. Garcia-Luis J, et al. Nat Struct Mol Biol. 2019 Oct;26(10):970-979. doi: 10.1038/s41594-019-0307-x. Epub 2019 Oct 3. Nat Struct Mol Biol. 2019. PMID: 31582854 Free PMC article.

2

Nondisjunction of a single chromosome leads to breakage and activation of DNA damage checkpoint in G2.

Quevedo O, García-Luis J, Matos-Perdomo E, Aragón L, Machín F. Quevedo O, et al. PLoS Genet. 2012;8(2):e1002509. doi: 10.1371/journal.pgen.1002509. Epub 2012 Feb 16. PLoS Genet. 2012. PMID: 22363215 Free PMC article.

3

Cdc14 targets the Holliday junction resolvase Yen1 to the nucleus in early anaphase.

García-Luis J, Clemente-Blanco A, Aragón L, Machín F. García-Luis J, et al. Cell Cycle. 2014;13(9):1392-9. doi: 10.4161/cc.28370. Epub 2014 Mar 5. Cell Cycle. 2014. PMID: 24626187 Free PMC article.

4

Physical Proximity of Sister Chromatids Promotes Top2-Dependent Intertwining.

Sen N, Leonard J, Torres R, Garcia-Luis J, Palou-Marin G, Aragón L. Sen N, et al. Mol Cell. 2016 Oct 6;64(1):134-147. doi: 10.1016/j.molcel.2016.09.007. Mol Cell. 2016. PMID: 27716481 Free PMC article.

5

Depletion or cleavage of cohesin during anaphase differentially affects chromatin structure and segregation.

Garcia-Luis J, Bordelet H, Thierry A, Koszul R, Aragon L. Garcia-Luis J, et al. Elife. 2022 Oct 5;11:e80147. doi: 10.7554/eLife.80147. Elife. 2022. PMID: 36196991 Free PMC article.

6

Cdc14 phosphatase: warning, no delay allowed for chromosome segregation!

Machín F, Quevedo O, Ramos-Pérez C, García-Luis J. Machín F, et al. Curr Genet. 2016 Feb;62(1):7-13. doi: 10.1007/s00294-015-0502-1. Epub 2015 Jun 27. Curr Genet. 2016. PMID: 26116076 Free PMC article. Review.

7

No role of homologous recombination in dealing with β-lapachone cytotoxicity in yeast.

Quevedo O, García-Luis J, Lorenzo-Castrillejo I, Machín F. Quevedo O, et al. Chem Res Toxicol. 2011 Dec 19;24(12):2106-8. doi: 10.1021/tx2004618. Epub 2011 Nov 22. Chem Res Toxicol. 2011. PMID: 22091990

8

Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides.

Quintana-Espinoza P, García-Luis J, Amesty A, Martín-Rodríguez P, Lorenzo-Castrillejo I, Ravelo AG, Fernández-Pérez L, Machín F, Estévez-Braun A. Quintana-Espinoza P, et al. Bioorg Med Chem. 2013 Nov 1;21(21):6484-95. doi: 10.1016/j.bmc.2013.08.039. Epub 2013 Aug 29. Bioorg Med Chem. 2013. PMID: 24054489

9

Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage.

Ramos-Pérez C, Lorenzo-Castrillejo I, Quevedo O, García-Luis J, Matos-Perdomo E, Medina-Coello C, Estévez-Braun A, Machín F. Ramos-Pérez C, et al. Biochem Pharmacol. 2014 Nov 15;92(2):206-19. doi: 10.1016/j.bcp.2014.09.006. Epub 2014 Sep 21. Biochem Pharmacol. 2014. PMID: 25241291

10

Mus81-Mms4 and Yen1 resolve a novel anaphase bridge formed by noncanonical Holliday junctions.

García-Luis J, Machín F. García-Luis J, et al. Nat Commun. 2014 Dec 3;5:5652. doi: 10.1038/ncomms6652. Nat Commun. 2014. PMID: 25466415 Free article.

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