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Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX.
Grüner B, Brynda J, Das V, Šícha V, Štěpánková J, Nekvinda J, Holub J, Pospíšilová K, Fábry M, Pachl P, Král V, Kugler M, Mašek V, Medvedíková M, Matějková S, Nová A, Lišková B, Gurská S, Džubák P, Hajdúch M, Řezáčová P. Grüner B, et al. Among authors: holub j. J Med Chem. 2019 Nov 14;62(21):9560-9575. doi: 10.1021/acs.jmedchem.9b00945. Epub 2019 Oct 16. J Med Chem. 2019. PMID: 31568723
A Series of the Twelve-Vertex Ferratricarbollides [2-(eta(5)-C(5)H(5))-9-X-closo-2,1,7,9-FeC(3)B(8)H(10)] (Where X = H(2)N, MeHN, Me(2)N, Bu(t)()HN, Bu(t)()(Me)N). A Highly Stable Metallatricarbaborane System with Amine Functions in the Para Position to the Metal Center.
Holub J, Grüner B, Císarová I I, Fusek J, Plzák Z, Teixidor F, Viñas C, Stíbr B. Holub J, et al. Inorg Chem. 1999 Jun 14;38(12):2775-2780. doi: 10.1021/ic981400e. Inorg Chem. 1999. PMID: 11671021
Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
Dvořanová J, Kugler M, Holub J, Šícha V, Das V, Nekvinda J, El Anwar S, Havránek M, Pospíšilová K, Fábry M, Král V, Medvedíková M, Matějková S, Lišková B, Gurská S, Džubák P, Brynda J, Hajdúch M, Grüner B, Řezáčová P. Dvořanová J, et al. Among authors: holub j. Eur J Med Chem. 2020 Aug 15;200:112460. doi: 10.1016/j.ejmech.2020.112460. Epub 2020 May 18. Eur J Med Chem. 2020. PMID: 32505851
Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Dicarba-closo-dodecaboranes: The Influence of Stereochemistry on Inhibitory Activity against the Cancer-Associated Carbonic Anhydrase IX Isoenzyme.
Nekvinda J, Kugler M, Holub J, El Anwar S, Brynda J, Pospíšilová K, Růžičková Z, Řezáčová P, Grüner B. Nekvinda J, et al. Among authors: holub j. Chemistry. 2020 Dec 9;26(69):16541-16553. doi: 10.1002/chem.202002809. Epub 2020 Nov 3. Chemistry. 2020. PMID: 32757220
274 results