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Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus.
Reeve SM, Si D, Krucinska J, Yan Y, Viswanathan K, Wang S, Holt GT, Frenkel MS, Ojewole AA, Estrada A, Agabiti SS, Alverson JB, Gibson ND, Priestley ND, Wiemer AJ, Donald BR, Wright DL. Reeve SM, et al. Among authors: viswanathan k. ACS Infect Dis. 2019 Nov 8;5(11):1896-1906. doi: 10.1021/acsinfecdis.9b00222. Epub 2019 Oct 15. ACS Infect Dis. 2019. PMID: 31565920 Free PMC article.
Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata.
G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC. G-Dayanandan N, et al. Among authors: viswanathan k. J Med Chem. 2014 Mar 27;57(6):2643-56. doi: 10.1021/jm401916j. Epub 2014 Mar 6. J Med Chem. 2014. PMID: 24568657 Free PMC article.
Drugging the Folate Pathway in Mycobacterium tuberculosis: The Role of Multi-targeting Agents.
Hajian B, Scocchera E, Shoen C, Krucinska J, Viswanathan K, G-Dayanandan N, Erlandsen H, Estrada A, Mikušová K, Korduláková J, Cynamon M, Wright D. Hajian B, et al. Among authors: viswanathan k. Cell Chem Biol. 2019 Jun 20;26(6):781-791.e6. doi: 10.1016/j.chembiol.2019.02.013. Epub 2019 Mar 28. Cell Chem Biol. 2019. PMID: 30930162 Free PMC article.
Viridin analogs derived from steroidal building blocks.
Viswanathan K, Ononye SN, Cooper HD, Kyle Hadden M, Anderson AC, Wright DL. Viswanathan K, et al. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6919-22. doi: 10.1016/j.bmcl.2012.09.015. Epub 2012 Sep 13. Bioorg Med Chem Lett. 2012. PMID: 23040731
344 results