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Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus.
Reeve SM, Si D, Krucinska J, Yan Y, Viswanathan K, Wang S, Holt GT, Frenkel MS, Ojewole AA, Estrada A, Agabiti SS, Alverson JB, Gibson ND, Priestley ND, Wiemer AJ, Donald BR, Wright DL. Reeve SM, et al. Among authors: priestley nd. ACS Infect Dis. 2019 Nov 8;5(11):1896-1906. doi: 10.1021/acsinfecdis.9b00222. Epub 2019 Oct 15. ACS Infect Dis. 2019. PMID: 31565920 Free PMC article.
Natural product derivatives with bactericidal activity against Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis.
Phillips JB, Smith AE, Kusche BR, Bessette BA Jr, Swain PW 3rd, Bergmeier SC, McMills MC, Wright DL, Priestley ND. Phillips JB, et al. Among authors: priestley nd. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5936-8. doi: 10.1016/j.bmcl.2010.06.146. Epub 2010 Jul 7. Bioorg Med Chem Lett. 2010. PMID: 20801034 Free PMC article.
Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata.
G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC. G-Dayanandan N, et al. Among authors: priestley nd. J Med Chem. 2014 Mar 27;57(6):2643-56. doi: 10.1021/jm401916j. Epub 2014 Mar 6. J Med Chem. 2014. PMID: 24568657 Free PMC article.
Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse.
Hoody J, Alverson JB, Keshipeddy S, Barney PA, Walker L, Anderson AC, Wright DL, Priestley ND. Hoody J, et al. Among authors: priestley nd. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Apr 15;1051:54-59. doi: 10.1016/j.jchromb.2017.02.026. Epub 2017 Mar 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28314188 Free PMC article.
41 results