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Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus.
Reeve SM, Si D, Krucinska J, Yan Y, Viswanathan K, Wang S, Holt GT, Frenkel MS, Ojewole AA, Estrada A, Agabiti SS, Alverson JB, Gibson ND, Priestley ND, Wiemer AJ, Donald BR, Wright DL. Reeve SM, et al. Among authors: holt gt. ACS Infect Dis. 2019 Nov 8;5(11):1896-1906. doi: 10.1021/acsinfecdis.9b00222. Epub 2019 Oct 15. ACS Infect Dis. 2019. PMID: 31565920 Free PMC article.
OSPREY 3.0: Open-source protein redesign for you, with powerful new features.
Hallen MA, Martin JW, Ojewole A, Jou JD, Lowegard AU, Frenkel MS, Gainza P, Nisonoff HM, Mukund A, Wang S, Holt GT, Zhou D, Dowd E, Donald BR. Hallen MA, et al. Among authors: holt gt. J Comput Chem. 2018 Nov 15;39(30):2494-2507. doi: 10.1002/jcc.25522. Epub 2018 Oct 14. J Comput Chem. 2018. PMID: 30368845 Free PMC article.
Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus.
Wang S, Reeve SM, Holt GT, Ojewole AA, Frenkel MS, Gainza P, Keshipeddy S, Fowler VG, Wright DL, Donald BR. Wang S, et al. Among authors: holt gt. PLoS Comput Biol. 2022 Feb 10;18(2):e1009855. doi: 10.1371/journal.pcbi.1009855. eCollection 2022 Feb. PLoS Comput Biol. 2022. PMID: 35143481 Free PMC article.
Improved methods for marking active neuron populations.
Moeyaert B, Holt G, Madangopal R, Perez-Alvarez A, Fearey BC, Trojanowski NF, Ledderose J, Zolnik TA, Das A, Patel D, Brown TA, Sachdev RNS, Eickholt BJ, Larkum ME, Turrigiano GG, Dana H, Gee CE, Oertner TG, Hope BT, Schreiter ER. Moeyaert B, et al. Nat Commun. 2018 Oct 25;9(1):4440. doi: 10.1038/s41467-018-06935-2. Nat Commun. 2018. PMID: 30361563 Free PMC article.
Sensitive red protein calcium indicators for imaging neural activity.
Dana H, Mohar B, Sun Y, Narayan S, Gordus A, Hasseman JP, Tsegaye G, Holt GT, Hu A, Walpita D, Patel R, Macklin JJ, Bargmann CI, Ahrens MB, Schreiter ER, Jayaraman V, Looger LL, Svoboda K, Kim DS. Dana H, et al. Among authors: holt gt. Elife. 2016 Mar 24;5:e12727. doi: 10.7554/eLife.12727. Elife. 2016. PMID: 27011354 Free PMC article.
11 results