Waisbourd-Zinman O - Search Results

1

Coordinated development of the mouse extrahepatic bile duct: Implications for neonatal susceptibility to biliary injury.

Khandekar G, Llewellyn J, Kriegermeier A, Waisbourd-Zinman O, Johnson N, Du Y, Giwa R, Liu X, Kisseleva T, Russo PA, Theise ND, Wells RG. Khandekar G, et al. J Hepatol. 2020 Jan;72(1):135-145. doi: 10.1016/j.jhep.2019.08.036. Epub 2019 Sep 25. J Hepatol. 2020. PMID: 31562906 Free PMC article.

2

Identification of a plant isoflavonoid that causes biliary atresia.

Lorent K, Gong W, Koo KA, Waisbourd-Zinman O, Karjoo S, Zhao X, Sealy I, Kettleborough RN, Stemple DL, Windsor PA, Whittaker SJ, Porter JR, Wells RG, Pack M. Lorent K, et al. Sci Transl Med. 2015 May 6;7(286):286ra67. doi: 10.1126/scitranslmed.aaa1652. Sci Transl Med. 2015. PMID: 25947162 Free PMC article.

3

Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids.

Koo KA, Waisbourd-Zinman O, Wells RG, Pack M, Porter JR. Koo KA, et al. Chem Res Toxicol. 2016 Feb 15;29(2):142-9. doi: 10.1021/acs.chemrestox.5b00308. Epub 2016 Jan 13. Chem Res Toxicol. 2016. PMID: 26713899 Free PMC article.

4

The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17.

Waisbourd-Zinman O, Koh H, Tsai S, Lavrut PM, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG. Waisbourd-Zinman O, et al. Hepatology. 2016 Sep;64(3):880-93. doi: 10.1002/hep.28599. Epub 2016 May 20. Hepatology. 2016. PMID: 27081925 Free PMC article.

5

Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish.

Zhao X, Lorent K, Wilkins BJ, Marchione DM, Gillespie K, Waisbourd-Zinman O, So J, Koo KA, Shin D, Porter JR, Wells RG, Blair I, Pack M. Zhao X, et al. Hepatology. 2016 Sep;64(3):894-907. doi: 10.1002/hep.28603. Epub 2016 Jun 11. Hepatology. 2016. PMID: 27102575 Free PMC article.

6

A Rare BSEP Mutation Associated with a Mild Form of Progressive Familial Intrahepatic Cholestasis Type 2.

Waisbourd-Zinman O, Surrey LF, Schwartz AE, Russo PA, Wen J. Waisbourd-Zinman O, et al. Ann Hepatol. 2017 May-Jun;16(3):465-468. doi: 10.5604/16652681.1235494. Ann Hepatol. 2017. PMID: 28425419 Free article.

7

A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1.

Chen Y, Gilbert MA, Grochowski CM, McEldrew D, Llewellyn J, Waisbourd-Zinman O, Hakonarson H, Bailey-Wilson JE, Russo P, Wells RG, Loomes KM, Spinner NB, Devoto M. Chen Y, et al. PLoS Genet. 2018 Aug 13;14(8):e1007532. doi: 10.1371/journal.pgen.1007532. eCollection 2018 Aug. PLoS Genet. 2018. PMID: 30102696 Free PMC article.

8

Recent advances in understanding biliary atresia.

Wehrman A, Waisbourd-Zinman O, Wells RG. Wehrman A, et al. F1000Res. 2019 Feb 25;8:F1000 Faculty Rev-218. doi: 10.12688/f1000research.16732.1. eCollection 2019. F1000Res. 2019. PMID: 30828434 Free PMC article. Review.

9

Extrahepatic cholangiocyte obstruction is mediated by decreased glutathione, Wnt and Notch signaling pathways in a toxic model of biliary atresia.

Fried S, Gilboa D, Har-Zahav A, Lavrut PM, Du Y, Karjoo S, Russo P, Shamir R, Wells RG, Waisbourd-Zinman O. Fried S, et al. Sci Rep. 2020 May 5;10(1):7599. doi: 10.1038/s41598-020-64503-5. Sci Rep. 2020. PMID: 32371929 Free PMC article.

10

Periductal bile acid exposure causes cholangiocyte injury and fibrosis.

Dotan M, Fried S, Har-Zahav A, Shamir R, Wells RG, Waisbourd-Zinman O. Dotan M, et al. PLoS One. 2022 Mar 16;17(3):e0265418. doi: 10.1371/journal.pone.0265418. eCollection 2022. PLoS One. 2022. PMID: 35294492 Free PMC article.

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