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Page 1
TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice.
Erkert L, Ruder B, Kabisch M, Gamez Belmonte R, Patankar JV, Gonzalez Acera M, Schödel L, Chiriac MT, Cineus R, Gnafakis S, Leupold T, Thoma OM, Stolzer I, Taut A, Thonn V, Zundler S, Günther C, Diefenbach A, Kühl AA, Hegazy AN, Waldner M, Basic M, Bleich A; TRR241 IBDome Consortium. Erkert L, et al. Mucosal Immunol. 2025 Jan 20:S1933-0219(25)00003-0. doi: 10.1016/j.mucimm.2025.01.003. Online ahead of print. Mucosal Immunol. 2025. PMID: 39842611 Free article.
Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease.
Bao LL, Yu YQ, González-Acera M, Patankar JV, Giessl A, Sturm G, Kühl AA, Atreya R, Erkert L, Gámez-Belmonte R, Krug SM, Schmid B, Tripal P, Chiriac MT, Hildner K, Siegmund B, Wirtz S, Stürzl M, Mohamed Abdou M, Trajanoski Z; TRR241 IBDome Consortium; Neurath MF, Zorzano A, Becker C. Bao LL, et al. Among authors: erkert l. Sci Transl Med. 2025 Jan 15;17(781):eadn8699. doi: 10.1126/scitranslmed.adn8699. Epub 2025 Jan 15. Sci Transl Med. 2025. PMID: 39813315
IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling.
Chiriac MT, Hracsko Z, Günther C, Gonzalez-Acera M, Atreya R, Stolzer I, Wittner L, Dressel A, Schickedanz L, Gamez-Belmonte R, Erkert L, Hundorfean G, Zundler S, Rath T, Vetrano S, Danese S, Sturm G, Trajanoski Z, Kühl AA, Siegmund B, Hartmann A, Wirtz S, Siebler J, Finotto S, Becker C, Neurath MF. Chiriac MT, et al. Among authors: erkert l. Gut. 2024 Jan 5;73(2):282-297. doi: 10.1136/gutjnl-2023-329628. Gut. 2024. PMID: 37884352 Free PMC article.
Analysis of the interferon-γ-induced secretome of intestinal endothelial cells: putative impact on epithelial barrier dysfunction in IBD.
Naschberger E, Flierl C, Huang J, Erkert L, Gamez-Belmonte R, Gonzalez-Acera M, Bober M, Mehnert M, Becker C, Schellerer VS, Britzen-Laurent N, Stürzl M. Naschberger E, et al. Among authors: erkert l. Front Cell Dev Biol. 2023 Aug 14;11:1213383. doi: 10.3389/fcell.2023.1213383. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37645250 Free PMC article.
Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling.
Gamez-Belmonte R, Mahapatro M, Erkert L, Gonzalez-Acera M, Naschberger E, Yu Y, Tena-Garitaonaindia M, Patankar JV, Wagner Y, Podstawa E, Schödel L, Bubeck M, Neurath MF, Stürzl M, Becker C. Gamez-Belmonte R, et al. Among authors: erkert l. Gut. 2023 Jun;72(6):1155-1166. doi: 10.1136/gutjnl-2022-327323. Epub 2022 Oct 19. Gut. 2023. PMID: 36261293
Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice.
Tisch N, Mogler C, Stojanovic A, Luck R, Korhonen EA, Ellerkmann A, Adler H, Singhal M, Schermann G, Erkert L, Patankar JV, Karakatsani A, Scherr AL, Fuchs Y, Cerwenka A, Wirtz S, Köhler BC, Augustin HG, Becker C, Schmidt T, Ruiz de Almodóvar C. Tisch N, et al. Among authors: erkert l. EMBO Mol Med. 2022 Jun 8;14(6):e14121. doi: 10.15252/emmm.202114121. Epub 2022 May 2. EMBO Mol Med. 2022. PMID: 35491615 Free PMC article.
Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation.
Martínez-Sánchez LDC, Ngo PA, Pradhan R, Becker LS, Boehringer D, Soteriou D, Kubankova M, Schweitzer C, Koch T, Thonn V, Erkert L, Stolzer I, Günther C, Becker C, Weigmann B, Klewer M, Daniel C, Amann K, Tenzer S, Atreya R, Bergo M, Brakebusch C, Watson AJM, Guck J, Fabry B, Atreya I, Neurath MF, López-Posadas R. Martínez-Sánchez LDC, et al. Among authors: erkert l. Gut. 2023 Feb;72(2):275-294. doi: 10.1136/gutjnl-2021-325520. Epub 2022 Mar 3. Gut. 2023. PMID: 35241625 Free PMC article.
17 results