Alvarez R - Search Results

1

Alkynyl Gold(I) complexes derived from 3-hydroxyflavones as multi-targeted drugs against colon cancer.

Mármol I, Castellnou P, Alvarez R, Gimeno MC, Rodríguez-Yoldi MJ, Cerrada E. Mármol I, et al. Among authors: alvarez r. Eur J Med Chem. 2019 Dec 1;183:111661. doi: 10.1016/j.ejmech.2019.111661. Epub 2019 Sep 7. Eur J Med Chem. 2019. PMID: 31546196

2

Endowing indole-based tubulin inhibitors with an anchor for derivatization: highly potent 3-substituted indolephenstatins and indoleisocombretastatins.

Álvarez R, Puebla P, Díaz JF, Bento AC, García-Navas R, de la Iglesia-Vicente J, Mollinedo F, Andreu JM, Medarde M, Peláez R. Álvarez R, et al. J Med Chem. 2013 Apr 11;56(7):2813-27. doi: 10.1021/jm3015603. Epub 2013 Mar 20. J Med Chem. 2013. PMID: 23470139

3

Exploring the size adaptability of the B ring binding zone of the colchicine site of tubulin with para-nitrogen substituted isocombretastatins.

Jiménez C, Ellahioui Y, Álvarez R, Aramburu L, Riesco A, González M, Vicente A, Dahdouh A, Ibn Mansour A, Jiménez C, Martín D, Sarmiento RG, Medarde M, Caballero E, Peláez R. Jiménez C, et al. Among authors: alvarez r. Eur J Med Chem. 2015 Jul 15;100:210-22. doi: 10.1016/j.ejmech.2015.05.047. Epub 2015 Jun 4. Eur J Med Chem. 2015. PMID: 26092446

4

Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells.

Álvarez R, Gajate C, Puebla P, Mollinedo F, Medarde M, Peláez R. Álvarez R, et al. Eur J Med Chem. 2018 Oct 5;158:167-183. doi: 10.1016/j.ejmech.2018.08.078. Epub 2018 Aug 31. Eur J Med Chem. 2018. PMID: 30216850

5

Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents.

Fuentes-Martín R, Ayuda-Durán P, Hanes R, Gallego-Yerga L, Wolterinck L, Enserink JM, Álvarez R, Peláez R. Fuentes-Martín R, et al. Among authors: alvarez r. Eur J Med Chem. 2024 Sep 5;275:116617. doi: 10.1016/j.ejmech.2024.116617. Epub 2024 Jun 27. Eur J Med Chem. 2024. PMID: 38959729 Free article.

6

1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity.

Alvarez R, Velázquez S, San-Félix A, Aquaro S, De Clercq E, Perno CF, Karlsson A, Balzarini J, Camarasa MJ. Alvarez R, et al. J Med Chem. 1994 Nov 25;37(24):4185-94. doi: 10.1021/jm00050a015. J Med Chem. 1994. PMID: 7527463

7

Synthesis and anti-HIV activity of [AZT]-[TSAO-T] and [AZT]-[HEPT] dimers as potential multifunctional inhibitors of HIV-1 reverse transcriptase.

Velázquez S, Alvarez R, San-Félix A, Jimeno ML, De Clercq E, Balzarini J, Camarasa MJ. Velázquez S, et al. Among authors: alvarez r. J Med Chem. 1995 May 12;38(10):1641-9. doi: 10.1021/jm00010a008. J Med Chem. 1995. PMID: 7538589

8

Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase.

Velázquez S, Chamorro C, Pérez-Pérez MJ, Alvarez R, Jimeno ML, Martín-Domenech A, Pérez C, Gago F, De Clercq E, Balzarini J, San-Félix A, Camarasa MJ. Velázquez S, et al. Among authors: alvarez r. J Med Chem. 1998 Nov 5;41(23):4636-47. doi: 10.1021/jm980370m. J Med Chem. 1998. PMID: 9804703 Free article.

9

Exploring the effect of 2,3,4-trimethoxy-phenyl moiety as a component of indolephenstatins.

Alvarez C, Alvarez R, Corchete P, Pérez-Melero C, Peláez R, Medarde M. Alvarez C, et al. Among authors: alvarez r. Eur J Med Chem. 2010 Feb;45(2):588-97. doi: 10.1016/j.ejmech.2009.10.047. Epub 2009 Nov 3. Eur J Med Chem. 2010. PMID: 19939521

10

Pyridine Based Antitumour Compounds Acting at the Colchicine Site.

Álvarez R, Aramburu L, Puebla P, Caballero E, González M, Vicente A, Medarde M, Peláez R. Álvarez R, et al. Curr Med Chem. 2016;23(11):1100-30. doi: 10.2174/092986732311160420104823. Curr Med Chem. 2016. PMID: 27117490 Review.

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