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Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers.
Sérandour AA, Avner S, Percevault F, Demay F, Bizot M, Lucchetti-Miganeh C, Barloy-Hubler F, Brown M, Lupien M, Métivier R, Salbert G, Eeckhoute J. Sérandour AA, et al. Among authors: lupien m. Genome Res. 2011 Apr;21(4):555-65. doi: 10.1101/gr.111534.110. Epub 2011 Jan 13. Genome Res. 2011. PMID: 21233399 Free PMC article.
The histone variant H2A.Z is an important regulator of enhancer activity.
Brunelle M, Nordell Markovits A, Rodrigue S, Lupien M, Jacques PÉ, Gévry N. Brunelle M, et al. Among authors: lupien m. Nucleic Acids Res. 2015 Nov 16;43(20):9742-56. doi: 10.1093/nar/gkv825. Epub 2015 Aug 28. Nucleic Acids Res. 2015. PMID: 26319018 Free PMC article.
PharmacoGx: an R package for analysis of large pharmacogenomic datasets.
Smirnov P, Safikhani Z, El-Hachem N, Wang D, She A, Olsen C, Freeman M, Selby H, Gendoo DM, Grossmann P, Beck AH, Aerts HJ, Lupien M, Goldenberg A, Haibe-Kains B. Smirnov P, et al. Among authors: lupien m. Bioinformatics. 2016 Apr 15;32(8):1244-6. doi: 10.1093/bioinformatics/btv723. Epub 2015 Dec 9. Bioinformatics. 2016. PMID: 26656004
Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer.
Bailey SD, Desai K, Kron KJ, Mazrooei P, Sinnott-Armstrong NA, Treloar AE, Dowar M, Thu KL, Cescon DW, Silvester J, Yang SY, Wu X, Pezo RC, Haibe-Kains B, Mak TW, Bedard PL, Pugh TJ, Sallari RC, Lupien M. Bailey SD, et al. Among authors: lupien m. Nat Genet. 2016 Oct;48(10):1260-6. doi: 10.1038/ng.3650. Epub 2016 Aug 29. Nat Genet. 2016. PMID: 27571262 Free PMC article.
150 results