Fischer M - Search Results

1

Water Networks Can Determine the Affinity of Ligand Binding to Proteins.

Darby JF, Hopkins AP, Shimizu S, Roberts SM, Brannigan JA, Turkenburg JP, Thomas GH, Hubbard RE, Fischer M. Darby JF, et al. Among authors: fischer m. J Am Chem Soc. 2019 Oct 9;141(40):15818-15826. doi: 10.1021/jacs.9b06275. Epub 2019 Sep 26. J Am Chem Soc. 2019. PMID: 31518131

2

Fragment-based ligand discovery.

Fischer M, Hubbard RE. Fischer M, et al. Mol Interv. 2009 Feb;9(1):22-30. doi: 10.1124/mi.9.1.7. Mol Interv. 2009. PMID: 19299661 Review.

3

Tripartite ATP-independent periplasmic (TRAP) transporters in bacteria and archaea.

Mulligan C, Fischer M, Thomas GH. Mulligan C, et al. Among authors: fischer m. FEMS Microbiol Rev. 2011 Jan;35(1):68-86. doi: 10.1111/j.1574-6976.2010.00236.x. FEMS Microbiol Rev. 2011. PMID: 20584082 Free article. Review.

4

Caught in a TRAP: substrate-binding proteins in secondary transport.

Fischer M, Zhang QY, Hubbard RE, Thomas GH. Fischer M, et al. Trends Microbiol. 2010 Oct;18(10):471-8. doi: 10.1016/j.tim.2010.06.009. Epub 2010 Jul 23. Trends Microbiol. 2010. PMID: 20656493 Review.

5

Comparative assessment of different histidine-tags for immobilization of protein onto surface plasmon resonance sensorchips.

Fischer M, Leech AP, Hubbard RE. Fischer M, et al. Anal Chem. 2011 Mar 1;83(5):1800-7. doi: 10.1021/ac103168q. Epub 2011 Feb 11. Anal Chem. 2011. PMID: 21314134

6

Tripartite ATP-independent Periplasmic (TRAP) Transporters Use an Arginine-mediated Selectivity Filter for High Affinity Substrate Binding.

Fischer M, Hopkins AP, Severi E, Hawkhead J, Bawdon D, Watts AG, Hubbard RE, Thomas GH. Fischer M, et al. J Biol Chem. 2015 Nov 6;290(45):27113-27123. doi: 10.1074/jbc.M115.656603. Epub 2015 Sep 5. J Biol Chem. 2015. PMID: 26342690 Free PMC article.

7

Hydrogen Bonding of 1,2-Azaborines in the Binding Cavity of T4 Lysozyme Mutants: Structures and Thermodynamics.

Lee H, Fischer M, Shoichet BK, Liu SY. Lee H, et al. Among authors: fischer m. J Am Chem Soc. 2016 Sep 21;138(37):12021-4. doi: 10.1021/jacs.6b06566. Epub 2016 Sep 12. J Am Chem Soc. 2016. PMID: 27603116 Free PMC article.

8

The Recognition of Unrelated Ligands by Identical Proteins.

Pottel J, Levit A, Korczynska M, Fischer M, Shoichet BK. Pottel J, et al. Among authors: fischer m. ACS Chem Biol. 2018 Sep 21;13(9):2522-2533. doi: 10.1021/acschembio.8b00443. Epub 2018 Aug 27. ACS Chem Biol. 2018. PMID: 30095890 Free PMC article.

9

Temperature artifacts in protein structures bias ligand-binding predictions.

Bradford SYC, El Khoury L, Ge Y, Osato M, Mobley DL, Fischer M. Bradford SYC, et al. Among authors: fischer m. Chem Sci. 2021 Jul 13;12(34):11275-11293. doi: 10.1039/d1sc02751d. eCollection 2021 Sep 1. Chem Sci. 2021. PMID: 34667539 Free PMC article.

10

Water Networks Repopulate Protein-Ligand Interfaces with Temperature.

Stachowski TR, Vanarotti M, Seetharaman J, Lopez K, Fischer M. Stachowski TR, et al. Among authors: fischer m. Angew Chem Int Ed Engl. 2022 Aug 1;61(31):e202112919. doi: 10.1002/anie.202112919. Epub 2022 Jun 21. Angew Chem Int Ed Engl. 2022. PMID: 35648650 Free PMC article.

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