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DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.
Samir P, Kesavardhana S, Patmore DM, Gingras S, Malireddi RKS, Karki R, Guy CS, Briard B, Place DE, Bhattacharya A, Sharma BR, Nourse A, King SV, Pitre A, Burton AR, Pelletier S, Gilbertson RJ, Kanneganti TD. Samir P, et al. Among authors: briard b. Nature. 2019 Sep;573(7775):590-594. doi: 10.1038/s41586-019-1551-2. Epub 2019 Sep 11. Nature. 2019. PMID: 31511697 Free PMC article.
DNA Sensing in the Innate Immune Response.
Briard B, Place DE, Kanneganti TD. Briard B, et al. Physiology (Bethesda). 2020 Mar 1;35(2):112-124. doi: 10.1152/physiol.00022.2019. Physiology (Bethesda). 2020. PMID: 32027562 Free PMC article. Review.
Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis).
Christgen S, Zheng M, Kesavardhana S, Karki R, Malireddi RKS, Banoth B, Place DE, Briard B, Sharma BR, Tuladhar S, Samir P, Burton A, Kanneganti TD. Christgen S, et al. Among authors: briard b. Front Cell Infect Microbiol. 2020 May 29;10:237. doi: 10.3389/fcimb.2020.00237. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32547960 Free PMC article.
Galactosaminogalactan activates the inflammasome to provide host protection.
Briard B, Fontaine T, Samir P, Place DE, Muszkieta L, Malireddi RKS, Karki R, Christgen S, Bomme P, Vogel P, Beau R, Mellado E, Ibrahim-Granet O, Henrissat B, Kalathur RC, Robinson C, Latgé JP, Kanneganti TD. Briard B, et al. Nature. 2020 Dec;588(7839):688-692. doi: 10.1038/s41586-020-2996-z. Epub 2020 Dec 2. Nature. 2020. PMID: 33268895 Free PMC article.
28 results