Chen X - Search Results

1

Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase.

Bonin JP, Sapienza PJ, Wilkerson E, Goldfarb D, Wang L, Herring L, Chen X, Major MB, Lee AL. Bonin JP, et al. Among authors: chen x. Biophys J. 2019 Sep 17;117(6):1074-1084. doi: 10.1016/j.bpj.2019.08.015. Epub 2019 Aug 22. Biophys J. 2019. PMID: 31500803 Free PMC article.

2

TBK1 Is a Synthetic Lethal Target in Cancer with VHL Loss.

Hu L, Xie H, Liu X, Potjewyd F, James LI, Wilkerson EM, Herring LE, Xie L, Chen X, Cabrera JC, Hong K, Liao C, Tan X, Baldwin AS, Gong K, Zhang Q. Hu L, et al. Among authors: chen x. Cancer Discov. 2020 Mar;10(3):460-475. doi: 10.1158/2159-8290.CD-19-0837. Epub 2019 Dec 6. Cancer Discov. 2020. PMID: 31810986 Free PMC article.

3

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.

Li Y, Wang L, Rivera-Serrano EE, Chen X, Lemon SM. Li Y, et al. Among authors: chen x. Nucleic Acids Res. 2019 Jul 9;47(12):6411-6424. doi: 10.1093/nar/gkz278. Nucleic Acids Res. 2019. PMID: 30997501 Free PMC article.

4

Protocol for proteogenomic dissection of intronic splicing enhancer interactome for prediction of individualized cancer prognosis.

Wang L, Wrobel JA, Xie L, Chen X. Wang L, et al. Among authors: chen x. STAR Protoc. 2021 Feb 11;2(1):100338. doi: 10.1016/j.xpro.2021.100338. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33644773 Free PMC article.

5

A Method to Generate and Analyze Modified Myristoylated Proteins.

Gao H, Sun W, Song Z, Yu Y, Wang L, Chen X, Zhang Q. Gao H, et al. Among authors: chen x. Chembiochem. 2017 Feb 1;18(3):324-330. doi: 10.1002/cbic.201600608. Epub 2017 Jan 3. Chembiochem. 2017. PMID: 27925692 Free PMC article.

6

Novel secretome-to-transcriptome integrated or secreto-transcriptomic approach to reveal liquid biopsy biomarkers for predicting individualized prognosis of breast cancer patients.

Ankney JA, Xie L, Wrobel JA, Wang L, Chen X. Ankney JA, et al. Among authors: chen x. BMC Med Genomics. 2019 May 30;12(1):78. doi: 10.1186/s12920-019-0530-7. BMC Med Genomics. 2019. PMID: 31146747 Free PMC article.

7

Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation.

Erdoğan Ö, Xie L, Wang L, Wu B, Kong Q, Wan Y, Chen X. Erdoğan Ö, et al. Among authors: chen x. Sci Rep. 2016 Apr 26;6:24833. doi: 10.1038/srep24833. Sci Rep. 2016. PMID: 27112199 Free PMC article.

8

Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader.

Wei J, Hu J, Wang L, Xie L, Jin MS, Chen X, Liu J, Jin J. Wei J, et al. Among authors: chen x. J Med Chem. 2019 Dec 12;62(23):10897-10911. doi: 10.1021/acs.jmedchem.9b01528. Epub 2019 Nov 27. J Med Chem. 2019. PMID: 31730343

9

Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX.

Wang L, Xie L, Ramachandran S, Lee Y, Yan Z, Zhou L, Krajewski K, Liu F, Zhu C, Chen DJ, Strahl BD, Jin J, Dokholyan NV, Chen X. Wang L, et al. Among authors: chen dj, chen x. Chem Biol. 2015 Jul 23;22(7):849-61. doi: 10.1016/j.chembiol.2015.05.014. Epub 2015 Jun 25. Chem Biol. 2015. PMID: 26119999 Free PMC article.

10

Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer.

Wang L, Wrobel JA, Xie L, Li D, Zurlo G, Shen H, Yang P, Wang Z, Peng Y, Gunawardena HP, Zhang Q, Chen X. Wang L, et al. Among authors: chen x. Cell Chem Biol. 2018 May 17;25(5):619-633.e5. doi: 10.1016/j.chembiol.2018.01.016. Epub 2018 Mar 1. Cell Chem Biol. 2018. PMID: 29503206 Free article.

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