Shen M - Search Results

1

Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.

Lee OW, Austin S, Gamma M, Cheff DM, Lee TD, Wilson KM, Johnson J, Travers J, Braisted JC, Guha R, Klumpp-Thomas C, Shen M, Hall MD. Lee OW, et al. Among authors: shen m. SLAS Discov. 2020 Jan;25(1):9-20. doi: 10.1177/2472555219873068. Epub 2019 Sep 9. SLAS Discov. 2020. PMID: 31498718 Free PMC article.

2

Firefly luciferase in chemical biology: a compendium of inhibitors, mechanistic evaluation of chemotypes, and suggested use as a reporter.

Thorne N, Shen M, Lea WA, Simeonov A, Lovell S, Auld DS, Inglese J. Thorne N, et al. Among authors: shen m. Chem Biol. 2012 Aug 24;19(8):1060-72. doi: 10.1016/j.chembiol.2012.07.015. Chem Biol. 2012. PMID: 22921073 Free PMC article.

3

A homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation.

Davis MI, Sasaki AT, Shen M, Emerling BM, Thorne N, Michael S, Pragani R, Boxer M, Sumita K, Takeuchi K, Auld DS, Li Z, Cantley LC, Simeonov A. Davis MI, et al. Among authors: shen m. PLoS One. 2013;8(1):e54127. doi: 10.1371/journal.pone.0054127. Epub 2013 Jan 10. PLoS One. 2013. PMID: 23326584 Free PMC article.

4

Identification of therapeutic candidates for chronic lymphocytic leukemia from a library of approved drugs.

Shen M, Zhang Y, Saba N, Austin CP, Wiestner A, Auld DS. Shen M, et al. PLoS One. 2013 Sep 20;8(9):e75252. doi: 10.1371/journal.pone.0075252. eCollection 2013. PLoS One. 2013. PMID: 24073257 Free PMC article.

5

High-throughput screening for the identification of new therapeutic options for metastatic pheochromocytoma and paraganglioma.

Giubellino A, Shankavaram U, Bullova P, Schovanek J, Zhang Y, Shen M, Patel N, Elkahloun A, Lee MJ, Trepel J, Ferrer M, Pacak K. Giubellino A, et al. Among authors: shen m. PLoS One. 2014 Apr 3;9(4):e90458. doi: 10.1371/journal.pone.0090458. eCollection 2014. PLoS One. 2014. PMID: 24699253 Free PMC article.

6

Research resource: modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay.

Blackford JA Jr, Brimacombe KR, Dougherty EJ, Pradhan M, Shen M, Li Z, Auld DS, Chow CC, Austin CP, Simons SS Jr. Blackford JA Jr, et al. Among authors: shen m. Mol Endocrinol. 2014 Jul;28(7):1194-206. doi: 10.1210/me.2014-1069. Epub 2014 May 21. Mol Endocrinol. 2014. PMID: 24850414 Free PMC article.

7

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer M, Lengyel E. Kenny HA, et al. Among authors: shen m. Nat Commun. 2015 Feb 5;6:6220. doi: 10.1038/ncomms7220. Nat Commun. 2015. PMID: 25653139 Free PMC article.

8

Diaphorase Coupling Protocols for Red-Shifting Dehydrogenase Assays.

Davis MI, Shen M, Simeonov A, Hall MD. Davis MI, et al. Among authors: shen m. Assay Drug Dev Technol. 2016 Apr;14(3):207-12. doi: 10.1089/adt.2016.706. Assay Drug Dev Technol. 2016. PMID: 27078681 Free PMC article.

9

Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Antiparasitic Activity.

Davis MI, Patrick SL, Blanding WM, Dwivedi V, Suryadi J, Golden JE, Coussens NP, Lee OW, Shen M, Boxer MB, Hall MD, Sharlow ER, Drew ME, Morris JC. Davis MI, et al. Among authors: shen m. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6023-33. doi: 10.1128/AAC.00914-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27458230 Free PMC article.

10

Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.

Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall MD, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A. Davis MI, et al. Among authors: shen m. J Biol Chem. 2016 Nov 18;291(47):24628-24640. doi: 10.1074/jbc.M116.738567. Epub 2016 Sep 28. J Biol Chem. 2016. PMID: 27681596 Free PMC article.

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