Sieber SA - Search Results

1

Acyldepsipeptide Probes Facilitate Specific Detection of Caseinolytic Protease P Independent of Its Oligomeric and Activity State.

Eyermann B, Meixner M, Brötz-Oesterhelt H, Antes I, Sieber SA. Eyermann B, et al. Among authors: sieber sa. Chembiochem. 2020 Jan 15;21(1-2):235-240. doi: 10.1002/cbic.201900477. Epub 2020 Jan 7. Chembiochem. 2020. PMID: 31487112 Free PMC article.

2

Insights into structural network responsible for oligomerization and activity of bacterial virulence regulator caseinolytic protease P (ClpP) protein.

Gersch M, List A, Groll M, Sieber SA. Gersch M, et al. Among authors: sieber sa. J Biol Chem. 2012 Mar 16;287(12):9484-94. doi: 10.1074/jbc.M111.336222. Epub 2012 Jan 30. J Biol Chem. 2012. PMID: 22291011 Free PMC article.

3

Rugulactone and its analogues exert antibacterial effects through multiple mechanisms including inhibition of thiamine biosynthesis.

Nodwell MB, Menz H, Kirsch SF, Sieber SA. Nodwell MB, et al. Among authors: sieber sa. Chembiochem. 2012 Jul 9;13(10):1439-46. doi: 10.1002/cbic.201200265. Epub 2012 May 31. Chembiochem. 2012. PMID: 22653914

4

The mechanism of caseinolytic protease (ClpP) inhibition.

Gersch M, Gut F, Korotkov VS, Lehmann J, Böttcher T, Rusch M, Hedberg C, Waldmann H, Klebe G, Sieber SA. Gersch M, et al. Among authors: sieber sa. Angew Chem Int Ed Engl. 2013 Mar 4;52(10):3009-14. doi: 10.1002/anie.201204690. Epub 2013 Jan 30. Angew Chem Int Ed Engl. 2013. PMID: 23361916 No abstract available.

5

Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition.

Gersch M, Kolb R, Alte F, Groll M, Sieber SA. Gersch M, et al. Among authors: sieber sa. J Am Chem Soc. 2014 Jan 29;136(4):1360-6. doi: 10.1021/ja4082793. Epub 2013 Oct 24. J Am Chem Soc. 2014. PMID: 24106749

6

A small molecule inhibits protein disulfide isomerase and triggers the chemosensitization of cancer cells.

Eirich J, Braig S, Schyschka L, Servatius P, Hoffmann J, Hecht S, Fulda S, Zahler S, Antes I, Kazmaier U, Sieber SA, Vollmar AM. Eirich J, et al. Among authors: sieber sa. Angew Chem Int Ed Engl. 2014 Nov 17;53(47):12960-5. doi: 10.1002/anie.201406577. Epub 2014 Sep 26. Angew Chem Int Ed Engl. 2014. PMID: 25256790

7

AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.

Gersch M, Famulla K, Dahmen M, Göbl C, Malik I, Richter K, Korotkov VS, Sass P, Rübsamen-Schaeff H, Madl T, Brötz-Oesterhelt H, Sieber SA. Gersch M, et al. Among authors: sieber sa. Nat Commun. 2015 Feb 19;6:6320. doi: 10.1038/ncomms7320. Nat Commun. 2015. PMID: 25695750 Free article.

8

Phenyl Esters Are Potent Inhibitors of Caseinolytic Protease P and Reveal a Stereogenic Switch for Deoligomerization.

Hackl MW, Lakemeyer M, Dahmen M, Glaser M, Pahl A, Lorenz-Baath K, Menzel T, Sievers S, Böttcher T, Antes I, Waldmann H, Sieber SA. Hackl MW, et al. Among authors: sieber sa. J Am Chem Soc. 2015 Jul 8;137(26):8475-83. doi: 10.1021/jacs.5b03084. Epub 2015 Jun 29. J Am Chem Soc. 2015. PMID: 26083639

9

Barrel-shaped ClpP Proteases Display Attenuated Cleavage Specificities.

Gersch M, Stahl M, Poreba M, Dahmen M, Dziedzic A, Drag M, Sieber SA. Gersch M, et al. Among authors: sieber sa. ACS Chem Biol. 2016 Feb 19;11(2):389-99. doi: 10.1021/acschembio.5b00757. Epub 2015 Dec 9. ACS Chem Biol. 2016. PMID: 26606371

10

Natural-Product-Inspired Aminoepoxybenzoquinones Kill Members of the Gram-Negative Pathogen Salmonella by Attenuating Cellular Stress Response.

Mandl FA, Kirsch VC, Ugur I, Kunold E, Vomacka J, Fetzer C, Schneider S, Richter K, Fuchs TM, Antes I, Sieber SA. Mandl FA, et al. Among authors: sieber sa. Angew Chem Int Ed Engl. 2016 Nov 14;55(47):14852-14857. doi: 10.1002/anie.201607338. Epub 2016 Oct 26. Angew Chem Int Ed Engl. 2016. PMID: 27782347

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