Brötz-Oesterhelt H - Search Results

1

Acyldepsipeptide Probes Facilitate Specific Detection of Caseinolytic Protease P Independent of Its Oligomeric and Activity State.

Eyermann B, Meixner M, Brötz-Oesterhelt H, Antes I, Sieber SA. Eyermann B, et al. Chembiochem. 2020 Jan 15;21(1-2):235-240. doi: 10.1002/cbic.201900477. Epub 2020 Jan 7. Chembiochem. 2020. PMID: 31487112 Free PMC article.

2

Sophisticated natural products as antibiotics.

Lewis K, Lee RE, Brötz-Oesterhelt H, Hiller S, Rodnina MV, Schneider T, Weingarth M, Wohlgemuth I. Lewis K, et al. Among authors: brotz oesterhelt h. Nature. 2024 Aug;632(8023):39-49. doi: 10.1038/s41586-024-07530-w. Epub 2024 Jul 31. Nature. 2024. PMID: 39085542 Free PMC article. Review.

3

Integrating research on bacterial pathogens and commensals to fight infections-an ecological perspective.

Maier L, Stein-Thoeringer C, Ley RE, Brötz-Oesterhelt H, Link H, Ziemert N, Wagner S, Peschel A. Maier L, et al. Among authors: brotz oesterhelt h. Lancet Microbe. 2024 Aug;5(8):100843. doi: 10.1016/S2666-5247(24)00049-1. Epub 2024 Apr 9. Lancet Microbe. 2024. PMID: 38608681 Free article. Review.

4

AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.

Gersch M, Famulla K, Dahmen M, Göbl C, Malik I, Richter K, Korotkov VS, Sass P, Rübsamen-Schaeff H, Madl T, Brötz-Oesterhelt H, Sieber SA. Gersch M, et al. Nat Commun. 2015 Feb 19;6:6320. doi: 10.1038/ncomms7320. Nat Commun. 2015. PMID: 25695750 Free article.

5

Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease.

Famulla K, Sass P, Malik I, Akopian T, Kandror O, Alber M, Hinzen B, Ruebsamen-Schaeff H, Kalscheuer R, Goldberg AL, Brötz-Oesterhelt H. Famulla K, et al. Mol Microbiol. 2016 Jul;101(2):194-209. doi: 10.1111/mmi.13362. Epub 2016 Apr 1. Mol Microbiol. 2016. PMID: 26919556 Free PMC article.

6

Activation of the glmS Ribozyme Confers Bacterial Growth Inhibition.

Schüller A, Matzner D, Lünse CE, Wittmann V, Schumacher C, Unsleber S, Brötz-Oesterhelt H, Mayer C, Bierbaum G, Mayer G. Schüller A, et al. Chembiochem. 2017 Mar 2;18(5):435-440. doi: 10.1002/cbic.201600491. Epub 2017 Jan 30. Chembiochem. 2017. PMID: 28012261

7

Conformational control of the bacterial Clp protease by natural product antibiotics.

Malik IT, Brötz-Oesterhelt H. Malik IT, et al. Nat Prod Rep. 2017 Jul 6;34(7):815-831. doi: 10.1039/c6np00125d. Nat Prod Rep. 2017. PMID: 28375422 Review.

8

Functional Characterisation of ClpP Mutations Conferring Resistance to Acyldepsipeptide Antibiotics in Firmicutes.

Malik IT, Pereira R, Vielberg MT, Mayer C, Straetener J, Thomy D, Famulla K, Castro H, Sass P, Groll M, Brötz-Oesterhelt H. Malik IT, et al. Chembiochem. 2020 Jul 16;21(14):1997-2012. doi: 10.1002/cbic.201900787. Epub 2020 Apr 9. Chembiochem. 2020. PMID: 32181548 Free PMC article.

9

New Nocobactin Derivatives with Antimuscarinic Activity, Terpenibactins A-C, Revealed by Genome Mining of Nocardia terpenica IFM 0406.

Chen J, Frediansyah A, Männle D, Straetener J, Brötz-Oesterhelt H, Ziemert N, Kaysser L, Gross H. Chen J, et al. Chembiochem. 2020 Aug 3;21(15):2205-2213. doi: 10.1002/cbic.202000062. Epub 2020 Apr 2. Chembiochem. 2020. PMID: 32196864 Free PMC article.

10

Cell Division Protein FtsZ Is Unfolded for N-Terminal Degradation by Antibiotic-Activated ClpP.

Silber N, Pan S, Schäkermann S, Mayer C, Brötz-Oesterhelt H, Sass P. Silber N, et al. mBio. 2020 Jun 30;11(3):e01006-20. doi: 10.1128/mBio.01006-20. mBio. 2020. PMID: 32605984 Free PMC article.

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