Pule MA - Search Results

1

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.

Ghorashian S, Kramer AM, Onuoha S, Wright G, Bartram J, Richardson R, Albon SJ, Casanovas-Company J, Castro F, Popova B, Villanueva K, Yeung J, Vetharoy W, Guvenel A, Wawrzyniecka PA, Mekkaoui L, Cheung GW, Pinner D, Chu J, Lucchini G, Silva J, Ciocarlie O, Lazareva A, Inglott S, Gilmour KC, Ahsan G, Ferrari M, Manzoor S, Champion K, Brooks T, Lopes A, Hackshaw A, Farzaneh F, Chiesa R, Rao K, Bonney D, Samarasinghe S, Goulden N, Vora A, Veys P, Hough R, Wynn R, Pule MA, Amrolia PJ. Ghorashian S, et al. Among authors: pule ma. Nat Med. 2019 Sep;25(9):1408-1414. doi: 10.1038/s41591-019-0549-5. Epub 2019 Sep 2. Nat Med. 2019. PMID: 31477906 Clinical Trial.

2

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma.

Pule MA, Savoldo B, Myers GD, Rossig C, Russell HV, Dotti G, Huls MH, Liu E, Gee AP, Mei Z, Yvon E, Weiss HL, Liu H, Rooney CM, Heslop HE, Brenner MK. Pule MA, et al. Nat Med. 2008 Nov;14(11):1264-70. doi: 10.1038/nm.1882. Epub 2008 Nov 2. Nat Med. 2008. PMID: 18978797 Free PMC article.

3

Generation of EBV-specific cytotoxic T cells that are resistant to calcineurin inhibitors for the treatment of posttransplantation lymphoproliferative disease.

Brewin J, Mancao C, Straathof K, Karlsson H, Samarasinghe S, Amrolia PJ, Pule M. Brewin J, et al. Blood. 2009 Nov 26;114(23):4792-803. doi: 10.1182/blood-2009-07-228387. Epub 2009 Sep 21. Blood. 2009. PMID: 19770360 Free article.

4

Functional characterization of alloreactive T cells identifies CD25 and CD71 as optimal targets for a clinically applicable allodepletion strategy.

Samarasinghe S, Mancao C, Pule M, Nawroly N, Karlsson H, Brewin J, Openshaw P, Gaspar HB, Veys P, Amrolia PJ. Samarasinghe S, et al. Blood. 2010 Jan 14;115(2):396-407. doi: 10.1182/blood-2009-08-235895. Epub 2009 Nov 4. Blood. 2010. PMID: 19890093 Free article.

5

Rapid generation of EBV-specific cytotoxic T lymphocytes resistant to calcineurin inhibitors for adoptive immunotherapy.

Ricciardelli I, Brewin J, Lugthart G, Albon SJ, Pule M, Amrolia PJ. Ricciardelli I, et al. Am J Transplant. 2013 Dec;13(12):3244-52. doi: 10.1111/ajt.12475. Epub 2013 Oct 8. Am J Transplant. 2013. PMID: 24266973 Free article.

6

Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells.

Ricciardelli I, Blundell MP, Brewin J, Thrasher A, Pule M, Amrolia PJ. Ricciardelli I, et al. Blood. 2014 Oct 16;124(16):2514-22. doi: 10.1182/blood-2014-01-553362. Epub 2014 Sep 2. Blood. 2014. PMID: 25185261 Free PMC article.

7

Chimeric antigen receptor T cells for ALL.

Amrolia PJ, Pule M. Amrolia PJ, et al. Lancet. 2015 Feb 7;385(9967):488-90. doi: 10.1016/S0140-6736(14)61729-3. Epub 2014 Oct 13. Lancet. 2015. PMID: 25319502 No abstract available.

8

CD19 chimeric antigen receptor T cell therapy for haematological malignancies.

Ghorashian S, Pule M, Amrolia P. Ghorashian S, et al. Br J Haematol. 2015 May;169(4):463-78. doi: 10.1111/bjh.13340. Epub 2015 Mar 5. Br J Haematol. 2015. PMID: 25753571 Free article. Review.

9

Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies.

Poirot L, Philip B, Schiffer-Mannioui C, Le Clerre D, Chion-Sotinel I, Derniame S, Potrel P, Bas C, Lemaire L, Galetto R, Lebuhotel C, Eyquem J, Cheung GW, Duclert A, Gouble A, Arnould S, Peggs K, Pule M, Scharenberg AM, Smith J. Poirot L, et al. Cancer Res. 2015 Sep 15;75(18):3853-64. doi: 10.1158/0008-5472.CAN-14-3321. Epub 2015 Jul 16. Cancer Res. 2015. PMID: 26183927

10

Automated manufacturing of chimeric antigen receptor T cells for adoptive immunotherapy using CliniMACS prodigy.

Mock U, Nickolay L, Philip B, Cheung GW, Zhan H, Johnston ICD, Kaiser AD, Peggs K, Pule M, Thrasher AJ, Qasim W. Mock U, et al. Cytotherapy. 2016 Aug;18(8):1002-1011. doi: 10.1016/j.jcyt.2016.05.009. Cytotherapy. 2016. PMID: 27378344

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