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Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.
Zhang L, He X, Liu X, Zhang F, Huang LF, Potter AS, Xu L, Zhou W, Zheng T, Luo Z, Berry KP, Pribnow A, Smith SM, Fuller C, Jones BV, Fouladi M, Drissi R, Yang ZJ, Gustafson WC, Remke M, Pomeroy SL, Girard EJ, Olson JM, Morrissy AS, Vladoiu MC, Zhang J, Tian W, Xin M, Taylor MD, Potter SS, Roussel MF, Weiss WA, Lu QR. Zhang L, et al. Among authors: yang zj. Cancer Cell. 2019 Sep 16;36(3):302-318.e7. doi: 10.1016/j.ccell.2019.07.009. Epub 2019 Aug 29. Cancer Cell. 2019. PMID: 31474569 Free PMC article.
Subtypes of medulloblastoma have distinct developmental origins.
Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ. Gibson P, et al. Among authors: yang zj. Nature. 2010 Dec 23;468(7327):1095-9. doi: 10.1038/nature09587. Epub 2010 Dec 8. Nature. 2010. PMID: 21150899 Free PMC article.
Astrocytes Promote Medulloblastoma Progression through Hedgehog Secretion.
Liu Y, Yuelling LW, Wang Y, Du F, Gordon RE, O'Brien JA, Ng JMY, Robins S, Lee EH, Liu H, Curran T, Yang ZJ. Liu Y, et al. Among authors: yang zj. Cancer Res. 2017 Dec 1;77(23):6692-6703. doi: 10.1158/0008-5472.CAN-17-1463. Epub 2017 Oct 6. Cancer Res. 2017. PMID: 28986380 Free PMC article.
Leukotriene Synthesis Is Critical for Medulloblastoma Progression.
Du F, Yuelling L, Lee EH, Wang Y, Liao S, Cheng Y, Zhang L, Zheng C, Peri S, Cai KQ, Ng JMY, Curran T, Li P, Yang ZJ. Du F, et al. Among authors: yang zj. Clin Cancer Res. 2019 Nov 1;25(21):6475-6486. doi: 10.1158/1078-0432.CCR-18-3549. Epub 2019 Jul 12. Clin Cancer Res. 2019. PMID: 31300449 Free PMC article.
NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma.
Cheng Y, Liao S, Xu G, Hu J, Guo D, Du F, Contreras A, Cai KQ, Peri S, Wang Y, Corney DC, Noronha AM, Chau LQ, Zhou G, Wiest DL, Bellacosa A, Wechsler-Reya RJ, Zhao Y, Yang ZJ. Cheng Y, et al. Among authors: yang zj. Cell Rep. 2020 Jun 23;31(12):107782. doi: 10.1016/j.celrep.2020.107782. Cell Rep. 2020. PMID: 32579914 Free PMC article.
928 results