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NK2 receptor-mediated detrusor muscle contraction involves Gq/11-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway.
Dér B, Molnár PJ, Ruisanchez É, Őrsy P, Kerék M, Faragó B, Nyirády P, Offermanns S, Benyó Z. Dér B, et al. Among authors: benyo z. Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1154-F1163. doi: 10.1152/ajprenal.00106.2019. Epub 2019 Aug 28. Am J Physiol Renal Physiol. 2019. PMID: 31461351 Free article.
GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.
Benyó Z, Gille A, Kero J, Csiky M, Suchánková MC, Nüsing RM, Moers A, Pfeffer K, Offermanns S. Benyó Z, et al. J Clin Invest. 2005 Dec;115(12):3634-40. doi: 10.1172/JCI23626. J Clin Invest. 2005. PMID: 16322797 Free PMC article.
Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(-/-) mice.
Buday A, Orsy P, Godó M, Mózes M, Kökény G, Lacza Z, Koller A, Ungvári Z, Gross ML, Benyó Z, Hamar P. Buday A, et al. Among authors: benyo z. Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H386-95. doi: 10.1152/ajpheart.01042.2009. Epub 2010 May 28. Am J Physiol Heart Circ Physiol. 2010. PMID: 20511416 Free PMC article.
Urothelial cells produce hydrogen peroxide through the activation of Duox1.
Donkó A, Ruisanchez E, Orient A, Enyedi B, Kapui R, Péterfi Z, de Deken X, Benyó Z, Geiszt M. Donkó A, et al. Among authors: benyo z. Free Radic Biol Med. 2010 Dec 15;49(12):2040-8. doi: 10.1016/j.freeradbiomed.2010.09.027. Free Radic Biol Med. 2010. PMID: 21146788
169 results