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A multifunctional AAV-CRISPR-Cas9 and its host response.
Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM. Chew WL, et al. Nat Methods. 2016 Oct;13(10):868-74. doi: 10.1038/nmeth.3993. Epub 2016 Sep 5. Nat Methods. 2016. PMID: 27595405 Free PMC article.
Engineering and optimising deaminase fusions for genome editing.
Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Yang L, et al. Among authors: chew wl. Nat Commun. 2016 Nov 2;7:13330. doi: 10.1038/ncomms13330. Nat Commun. 2016. PMID: 27804970 Free PMC article.
Robust genome and cell engineering via in vitro and in situ circularized RNAs.
Tong M, Palmer N, Dailamy A, Kumar A, Khaliq H, Han S, Finburgh E, Wing M, Hong C, Xiang Y, Miyasaki K, Portell A, Rainaldi J, Suhardjo A, Nourreddine S, Chew WL, Kwon EJ, Mali P. Tong M, et al. Among authors: chew wl. Nat Biomed Eng. 2024 Aug 26. doi: 10.1038/s41551-024-01245-z. Online ahead of print. Nat Biomed Eng. 2024. PMID: 39187662
Immunity to CRISPR Cas9 and Cas12a therapeutics.
Chew WL. Chew WL. Wiley Interdiscip Rev Syst Biol Med. 2018 Jan;10(1). doi: 10.1002/wsbm.1408. Epub 2017 Oct 30. Wiley Interdiscip Rev Syst Biol Med. 2018. PMID: 29083112 Review.
In vivo gene editing in dystrophic mouse muscle and muscle stem cells.
Tabebordbar M, Zhu K, Cheng JKW, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ. Tabebordbar M, et al. Among authors: chew wl. Science. 2016 Jan 22;351(6271):407-411. doi: 10.1126/science.aad5177. Epub 2015 Dec 31. Science. 2016. PMID: 26721686 Free PMC article.
38 results