Metcalf WW - Search Results

1

Fosmidomycin biosynthesis diverges from related phosphonate natural products.

Parkinson EI, Erb A, Eliot AC, Ju KS, Metcalf WW. Parkinson EI, et al. Among authors: metcalf ww. Nat Chem Biol. 2019 Nov;15(11):1049-1056. doi: 10.1038/s41589-019-0343-1. Epub 2019 Aug 26. Nat Chem Biol. 2019. PMID: 31451762 Free PMC article.

2

Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster.

Woodyer RD, Shao Z, Thomas PM, Kelleher NL, Blodgett JA, Metcalf WW, van der Donk WA, Zhao H. Woodyer RD, et al. Among authors: metcalf ww. Chem Biol. 2006 Nov;13(11):1171-82. doi: 10.1016/j.chembiol.2006.09.007. Chem Biol. 2006. PMID: 17113999

3

Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.

Blodgett JA, Thomas PM, Li G, Velasquez JE, van der Donk WA, Kelleher NL, Metcalf WW. Blodgett JA, et al. Among authors: metcalf ww. Nat Chem Biol. 2007 Aug;3(8):480-5. doi: 10.1038/nchembio.2007.9. Epub 2007 Jul 15. Nat Chem Biol. 2007. PMID: 17632514 Free PMC article.

4

Reassignment of the structure of the antibiotic A53868 reveals an unusual amino dehydrophosphonic acid.

Whitteck JT, Ni W, Griffin BM, Eliot AC, Thomas PM, Kelleher NL, Metcalf WW, van der Donk WA. Whitteck JT, et al. Among authors: metcalf ww. Angew Chem Int Ed Engl. 2007;46(47):9089-92. doi: 10.1002/anie.200703810. Angew Chem Int Ed Engl. 2007. PMID: 17990255 No abstract available.

5

Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways.

Shao Z, Blodgett JA, Circello BT, Eliot AC, Woodyer R, Li G, van der Donk WA, Metcalf WW, Zhao H. Shao Z, et al. Among authors: metcalf ww. J Biol Chem. 2008 Aug 22;283(34):23161-8. doi: 10.1074/jbc.M801788200. Epub 2008 Jun 10. J Biol Chem. 2008. PMID: 18544530 Free PMC article.

6

Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098.

Eliot AC, Griffin BM, Thomas PM, Johannes TW, Kelleher NL, Zhao H, Metcalf WW. Eliot AC, et al. Among authors: metcalf ww. Chem Biol. 2008 Aug 25;15(8):765-70. doi: 10.1016/j.chembiol.2008.07.010. Chem Biol. 2008. PMID: 18721747 Free PMC article.

7

Biosynthesis of phosphonic and phosphinic acid natural products.

Metcalf WW, van der Donk WA. Metcalf WW, et al. Annu Rev Biochem. 2009;78:65-94. doi: 10.1146/annurev.biochem.78.091707.100215. Annu Rev Biochem. 2009. PMID: 19489722 Free PMC article. Review.

8

An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis.

Cicchillo RM, Zhang H, Blodgett JA, Whitteck JT, Li G, Nair SK, van der Donk WA, Metcalf WW. Cicchillo RM, et al. Among authors: metcalf ww. Nature. 2009 Jun 11;459(7248):871-4. doi: 10.1038/nature07972. Nature. 2009. PMID: 19516340 Free PMC article.

9

Biosynthesis of rhizocticins, antifungal phosphonate oligopeptides produced by Bacillus subtilis ATCC6633.

Borisova SA, Circello BT, Zhang JK, van der Donk WA, Metcalf WW. Borisova SA, et al. Among authors: metcalf ww. Chem Biol. 2010 Jan 29;17(1):28-37. doi: 10.1016/j.chembiol.2009.11.017. Chem Biol. 2010. PMID: 20142038 Free PMC article.

10

Deciphering the late biosynthetic steps of antimalarial compound FR-900098.

Johannes TW, DeSieno MA, Griffin BM, Thomas PM, Kelleher NL, Metcalf WW, Zhao H. Johannes TW, et al. Among authors: metcalf ww. Chem Biol. 2010 Jan 29;17(1):57-64. doi: 10.1016/j.chembiol.2009.12.009. Chem Biol. 2010. PMID: 20142041 Free PMC article.

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