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Tulathromycin exerts proresolving effects in bovine neutrophils by inhibiting phospholipases and altering leukotriene B4, prostaglandin E2, and lipoxin A4 production.
Fischer CD, Duquette SC, Renaux BS, Feener TD, Morck DW, Hollenberg MD, Lucas MJ, Buret AG. Fischer CD, et al. Among authors: feener td. Antimicrob Agents Chemother. 2014 Aug;58(8):4298-307. doi: 10.1128/AAC.02813-14. Epub 2014 May 12. Antimicrob Agents Chemother. 2014. PMID: 24820086 Free PMC article.
Giardia spp. promote the production of antimicrobial peptides and attenuate disease severity induced by attaching and effacing enteropathogens via the induction of the NLRP3 inflammasome.
Manko-Prykhoda A, Allain T, Motta JP, Cotton JA, Feener T, Oyeyemi A, Bindra S, Vallance BA, Wallace JL, Beck P, Buret AG. Manko-Prykhoda A, et al. Int J Parasitol. 2020 Apr;50(4):263-275. doi: 10.1016/j.ijpara.2019.12.011. Epub 2020 Mar 14. Int J Parasitol. 2020. PMID: 32184085 Free article.
Immunomodulatory effects of tulathromycin on apoptosis, efferocytosis, and proinflammatory leukotriene B4 production in leukocytes from Actinobacillus pleuropneumoniae-or zymosan-challenged pigs.
Duquette SC, Fischer CD, Williams AC, Sajedy S, Feener TD, Bhargava A, Reti KL, Muench GP, Morck DW, Allison J, Lucas MJ, Buret AG. Duquette SC, et al. Among authors: feener td. Am J Vet Res. 2015 Jun;76(6):507-19. doi: 10.2460/ajvr.76.6.507. Am J Vet Res. 2015. PMID: 26000598 Free article.
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