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Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
Zhong W, Pasunooti KK, Balamkundu S, Wong YH, Nah Q, Gadi V, Gnanakalai S, Chionh YH, McBee ME, Gopal P, Lim SH, Olivier N, Buurman ET, Dick T, Liu CF, Lescar J, Dedon PC. Zhong W, et al. Among authors: dedon pc. J Med Chem. 2019 Sep 12;62(17):7788-7805. doi: 10.1021/acs.jmedchem.9b00582. Epub 2019 Aug 29. J Med Chem. 2019. PMID: 31442049 Free PMC article.
2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase.
Dong H, Chang DC, Hua MH, Lim SP, Chionh YH, Hia F, Lee YH, Kukkaro P, Lok SM, Dedon PC, Shi PY. Dong H, et al. Among authors: dedon pc. PLoS Pathog. 2012;8(4):e1002642. doi: 10.1371/journal.ppat.1002642. Epub 2012 Apr 5. PLoS Pathog. 2012. PMID: 22496660 Free PMC article.
A multidimensional platform for the purification of non-coding RNA species.
Chionh YH, Ho CH, Pruksakorn D, Ramesh Babu I, Ng CS, Hia F, McBee ME, Su D, Pang YL, Gu C, Dong H, Prestwich EG, Shi PY, Preiser PR, Alonso S, Dedon PC. Chionh YH, et al. Among authors: dedon pc. Nucleic Acids Res. 2013 Sep;41(17):e168. doi: 10.1093/nar/gkt668. Epub 2013 Aug 1. Nucleic Acids Res. 2013. PMID: 23907385 Free PMC article.
Mycobacterial RNA isolation optimized for non-coding RNA: high fidelity isolation of 5S rRNA from Mycobacterium bovis BCG reveals novel post-transcriptional processing and a complete spectrum of modified ribonucleosides.
Hia F, Chionh YH, Pang YL, DeMott MS, McBee ME, Dedon PC. Hia F, et al. Among authors: dedon pc. Nucleic Acids Res. 2015 Mar 11;43(5):e32. doi: 10.1093/nar/gku1317. Epub 2014 Dec 24. Nucleic Acids Res. 2015. PMID: 25539917 Free PMC article.
249 results