Schein CH - Search Results

1

Repurposing approved drugs on the pathway to novel therapies.

Schein CH. Schein CH. Med Res Rev. 2020 Mar;40(2):586-605. doi: 10.1002/med.21627. Epub 2019 Aug 20. Med Res Rev. 2020. PMID: 31432544 Free PMC article. Review.

2

Repurposing approved drugs for cancer therapy.

Schein CH. Schein CH. Br Med Bull. 2021 Mar 25;137(1):13-27. doi: 10.1093/bmb/ldaa045. Br Med Bull. 2021. PMID: 33517358 Free PMC article. Review.

3

Novel inhibitors of anthrax edema factor.

Chen D, Misra M, Sower L, Peterson JW, Kellogg GE, Schein CH. Chen D, et al. Among authors: schein ch. Bioorg Med Chem. 2008 Aug 1;16(15):7225-33. doi: 10.1016/j.bmc.2008.06.036. Epub 2008 Jun 28. Bioorg Med Chem. 2008. PMID: 18620864 Free PMC article.

4

Computational selection of inhibitors of Abeta aggregation and neuronal toxicity.

Chen D, Martin ZS, Soto C, Schein CH. Chen D, et al. Among authors: schein ch. Bioorg Med Chem. 2009 Jul 15;17(14):5189-97. doi: 10.1016/j.bmc.2009.05.047. Epub 2009 May 27. Bioorg Med Chem. 2009. PMID: 19540126 Free PMC article.

5

Structure-based redesign of an edema toxin inhibitor.

Chen D, Ma L, Kanalas JJ, Gao J, Pawlik J, Jimenez ME, Walter MA, Peterson JW, Gilbertson SR, Schein CH. Chen D, et al. Among authors: schein ch. Bioorg Med Chem. 2012 Jan 1;20(1):368-76. doi: 10.1016/j.bmc.2011.10.091. Epub 2011 Nov 16. Bioorg Med Chem. 2012. PMID: 22154558 Free PMC article.

6

Pharmacophore selection and redesign of non-nucleotide inhibitors of anthrax edema factor.

Schein CH, Chen D, Ma L, Kanalas JJ, Gao J, Jimenez ME, Sower LE, Walter MA, Gilbertson SR, Peterson JW. Schein CH, et al. Toxins (Basel). 2012 Nov 8;4(11):1288-300. doi: 10.3390/toxins4111288. Toxins (Basel). 2012. PMID: 23202316 Free PMC article. Review.

7

Allosteric inhibitors of Coxsackie virus A24 RNA polymerase.

Schein CH, Rowold D, Choi KH. Schein CH, et al. Bioorg Med Chem. 2016 Feb 15;24(4):570-7. doi: 10.1016/j.bmc.2015.12.023. Epub 2015 Dec 15. Bioorg Med Chem. 2016. PMID: 26762834 Free PMC article.

8

The shape of the messenger: using protein structure information to design novel cytokine-based therapeutics.

Schein CH. Schein CH. Curr Pharm Des. 2002;8(24):2113-29. doi: 10.2174/1381612023393161. Curr Pharm Des. 2002. PMID: 12369857 Review.

9

Using property based sequence motifs and 3D modeling to determine structure and functional regions of proteins.

Ivanciuc O, Oezguen N, Mathura VS, Schein CH, Xu Y, Braun W. Ivanciuc O, et al. Among authors: schein ch. Curr Med Chem. 2004 Mar;11(5):583-93. doi: 10.2174/0929867043455819. Curr Med Chem. 2004. PMID: 15032606 Review.

10

Polyglutamine Repeats in Viruses.

Schein CH. Schein CH. Mol Neurobiol. 2019 May;56(5):3664-3675. doi: 10.1007/s12035-018-1269-4. Epub 2018 Sep 4. Mol Neurobiol. 2019. PMID: 30182336 Free PMC article. Review.

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