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A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.
Nouri K, Azad T, Lightbody E, Khanal P, Nicol CJ, Yang X. Nouri K, et al. Among authors: khanal p. FASEB J. 2019 Nov;33(11):12487-12499. doi: 10.1096/fj.201901343R. Epub 2019 Aug 20. FASEB J. 2019. PMID: 31431076 Free PMC article.
In summary, we have developed a new LATS BS for cancer biology and therapeutics research and uncovered a novel ALK-LATS-YAP/TAZ signaling axis that may play important roles in cancer and possibly other biologic processes.-Nouri, K., Azad, T., Lightbody, E., Khanal, P …
In summary, we have developed a new LATS BS for cancer biology and therapeutics research and uncovered a novel ALK-LATS-YAP/TAZ signaling ax …
268 results