Sad S - Search Results

1

Ripk3 licenced protection against microbial infection in the absence of Caspase1-11 inflammasome.

Shutinoski B, Patel R, Tomlinson JJ, Schlossmacher MG, Sad S. Shutinoski B, et al. Among authors: sad s. Microbes Infect. 2020 Jan-Feb;22(1):40-45. doi: 10.1016/j.micinf.2019.08.002. Epub 2019 Aug 17. Microbes Infect. 2020. PMID: 31430539 Free article.

2

Salmonella enterica serovar Typhimurium-induced placental inflammation and not bacterial burden correlates with pathology and fatal maternal disease.

Chattopadhyay A, Robinson N, Sandhu JK, Finlay BB, Sad S, Krishnan L. Chattopadhyay A, et al. Among authors: sad s. Infect Immun. 2010 May;78(5):2292-301. doi: 10.1128/IAI.01186-09. Epub 2010 Mar 1. Infect Immun. 2010. PMID: 20194592 Free PMC article.

3

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium.

Robinson N, McComb S, Mulligan R, Dudani R, Krishnan L, Sad S. Robinson N, et al. Among authors: sad s. Nat Immunol. 2012 Oct;13(10):954-62. doi: 10.1038/ni.2397. Epub 2012 Aug 26. Nat Immunol. 2012. PMID: 22922364 Free PMC article.

4

Cathepsins limit macrophage necroptosis through cleavage of Rip1 kinase.

McComb S, Shutinoski B, Thurston S, Cessford E, Kumar K, Sad S. McComb S, et al. Among authors: sad s. J Immunol. 2014 Jun 15;192(12):5671-8. doi: 10.4049/jimmunol.1303380. Epub 2014 May 5. J Immunol. 2014. PMID: 24799565

5

Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.

McComb S, Cessford E, Alturki NA, Joseph J, Shutinoski B, Startek JB, Gamero AM, Mossman KL, Sad S. McComb S, et al. Among authors: sad s. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):E3206-13. doi: 10.1073/pnas.1407068111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049377 Free PMC article.

6

Transcription factor Batf3 is important for development of CD8+ T-cell response against a phagosomal bacterium regardless of the location of antigen.

Patel R, Sad S. Patel R, et al. Among authors: sad s. Immunol Cell Biol. 2016 Apr;94(4):378-87. doi: 10.1038/icb.2015.98. Epub 2015 Dec 8. Immunol Cell Biol. 2016. PMID: 26567886

7

Clinical Isolates of Pseudomonas aeruginosa from Chronically Infected Cystic Fibrosis Patients Fail To Activate the Inflammasome during Both Stable Infection and Pulmonary Exacerbation.

Huus KE, Joseph J, Zhang L, Wong A, Aaron SD, Mah TF, Sad S. Huus KE, et al. Among authors: sad s. J Immunol. 2016 Apr 1;196(7):3097-108. doi: 10.4049/jimmunol.1501642. Epub 2016 Feb 19. J Immunol. 2016. PMID: 26895832

8

K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo.

Shutinoski B, Alturki NA, Rijal D, Bertin J, Gough PJ, Schlossmacher MG, Sad S. Shutinoski B, et al. Among authors: sad s. Cell Death Differ. 2016 Oct;23(10):1628-37. doi: 10.1038/cdd.2016.51. Epub 2016 Jun 3. Cell Death Differ. 2016. PMID: 27258786 Free PMC article.

9

Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects.

Tomlinson JJ, Shutinoski B, Dong L, Meng F, Elleithy D, Lengacher NA, Nguyen AP, Cron GO, Jiang Q, Roberson ED, Nussbaum RL, Majbour NK, El-Agnaf OM, Bennett SA, Lagace DC, Woulfe JM, Sad S, Brown EG, Schlossmacher MG. Tomlinson JJ, et al. Among authors: sad s. J Neural Transm (Vienna). 2017 Jun;124(6):721-738. doi: 10.1007/s00702-017-1726-7. Epub 2017 May 5. J Neural Transm (Vienna). 2017. PMID: 28477284 Free PMC article.

10

Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells.

Patel R, Kim K, Shutinoski B, Wachholz K, Krishnan L, Sad S. Patel R, et al. Among authors: sad s. Cell Death Differ. 2017 Nov;24(11):1900-1911. doi: 10.1038/cdd.2017.112. Epub 2017 Jul 7. Cell Death Differ. 2017. PMID: 28686578 Free PMC article.

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