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IFN-γ-mediated reduction of large-conductance, Ca2+-activated, voltage-dependent K+ (BK) channel activity in airway epithelial cells leads to mucociliary dysfunction.
Manzanares D, Srinivasan M, Salathe ST, Ivonnet P, Baumlin N, Dennis JS, Conner GE, Salathe M. Manzanares D, et al. Among authors: salathe m, salathe st. Am J Physiol Lung Cell Mol Physiol. 2014 Mar 1;306(5):L453-62. doi: 10.1152/ajplung.00247.2013. Epub 2014 Jan 10. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24414257 Free PMC article.
Toxicity of aged gasoline exhaust particles to normal and diseased airway epithelia.
Künzi L, Krapf M, Daher N, Dommen J, Jeannet N, Schneider S, Platt S, Slowik JG, Baumlin N, Salathe M, Prévôt AS, Kalberer M, Strähl C, Dümbgen L, Sioutas C, Baltensperger U, Geiser M. Künzi L, et al. Among authors: salathe m. Sci Rep. 2015 Jun 29;5:11801. doi: 10.1038/srep11801. Sci Rep. 2015. PMID: 26119831 Free PMC article.
Airway Surface Dehydration by Transforming Growth Factor β (TGF-β) in Cystic Fibrosis Is Due to Decreased Function of a Voltage-dependent Potassium Channel and Can Be Rescued by the Drug Pirfenidone.
Manzanares D, Krick S, Baumlin N, Dennis JS, Tyrrell J, Tarran R, Salathe M. Manzanares D, et al. Among authors: salathe m. J Biol Chem. 2015 Oct 16;290(42):25710-6. doi: 10.1074/jbc.M115.670885. Epub 2015 Sep 3. J Biol Chem. 2015. PMID: 26338706 Free PMC article.
242 results