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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity.
Cell Rep. 2019 Aug 13;28(7):1879-1893.e7. doi: 10.1016/j.celrep.2019.07.044.
Cell Rep. 2019.
PMID: 31412253
Free PMC article.
Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response.
Vaena S, Chakraborty P, Lee HG, Janneh AH, Kassir MF, Beeson G, Hedley Z, Yalcinkaya A, Sofi MH, Li H, Husby ML, Stahelin RV, Yu XZ, Mehrotra S, Ogretmen B.
Vaena S, et al. Among authors: hedley z.
Cell Rep. 2021 May 4;35(5):109076. doi: 10.1016/j.celrep.2021.109076.
Cell Rep. 2021.
PMID: 33951438
Free PMC article.
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Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function.
Chakraborty P, Parikh RY, Choi S, Tran D, Gooz M, Hedley ZT, Kim DS, Pytel D, Kang I, Nadig SN, Beeson GC, Ball L, Mehrotra M, Wang H, Berto S, Palanisamy V, Li H, Chatterjee S, Rodriguez PC, Maldonado EN, Diehl JA, Gangaraju VK, Mehrotra S.
Chakraborty P, et al. Among authors: hedley zt.
Cancer Res. 2022 May 16;82(10):1969-1990. doi: 10.1158/0008-5472.CAN-21-3155.
Cancer Res. 2022.
PMID: 35404405
Free PMC article.
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H2S-Prdx4 axis mitigates Golgi stress to bolster tumor-reactive T cell immunotherapeutic response.
Oberholtzer N, Chakraborty P, Kassir MF, Dressman J, Das S, Mills S, Comte-Walters S, Gooz M, Choi S, Parikh RY, Hedley Z, Vaena S, DeMass R, Scurti G, Romeo M, Gangaraju VK, Berto S, Hill E, Ball LE, Mehta AS, Maldonado EN, Nishimura MI, Ogretmen B, Mehrotra S.
Oberholtzer N, et al. Among authors: hedley z.
Sci Adv. 2024 Nov 15;10(46):eadp1152. doi: 10.1126/sciadv.adp1152. Epub 2024 Nov 15.
Sci Adv. 2024.
PMID: 39546607
Free PMC article.
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