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Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions.
Brandolini L, d'Angelo M, Novelli R, Castelli V, Giorgio C, Sirico A, Cocchiaro P, D'Egidio F, Benedetti E, Cristiano C, Bugatti A, Ruocco A, Amendola PG, Talarico C, Manelfi C, Iaconis D, Beccari A, Quadros AU, Cunha TM, Caruso A, Russo R, Cimini A, Aramini A, Allegretti M. Brandolini L, et al. Among authors: giorgio c. Cell Death Dis. 2022 May 25;13(5):500. doi: 10.1038/s41419-022-04964-w. Cell Death Dis. 2022. PMID: 35614037 Free PMC article.
GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis.
Marino S, Finamore C, Biagioli M, Carino A, Marchianò S, Roselli R, Giorgio CD, Bordoni M, Di Leva FS, Novellino E, Cassiano C, Limongelli V, Zampella A, Festa C, Fiorucci S. Marino S, et al. Among authors: giorgio cd. ACS Med Chem Lett. 2020 Mar 2;11(5):818-824. doi: 10.1021/acsmedchemlett.9b00636. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435390 Free PMC article.
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions.
Biagioli M, Carino A, Fiorucci C, Annunziato G, Marchianò S, Bordoni M, Roselli R, Giorgio CD, Castiglione F, Ricci P, Bruno A, Faccini A, Distrutti E, Baldoni M, Costantino G, Fiorucci S. Biagioli M, et al. Among authors: giorgio cd. Nutrients. 2019 Aug 7;11(8):1820. doi: 10.3390/nu11081820. Nutrients. 2019. PMID: 31394746 Free PMC article.
Liver GPBAR1 Associates With Immune Dysfunction in Primary Sclerosing Cholangitis and Its Activation Attenuates Cholestasis in Abcb4-/- Mice.
Di Giorgio C, Urbani G, Marchianò S, Biagioli M, Bordoni M, Bellini R, Massa C, Lachi G, Cari L, Morretta E, Spinelli L, Monti MC, Sepe V, Zampella A, Distrutti E, Banales JM, Lapitz A, Milkiewicz P, Milkiewicz M, Fiorucci S. Di Giorgio C, et al. Liver Int. 2025 Feb;45(2):e16235. doi: 10.1111/liv.16235. Liver Int. 2025. PMID: 39804015 Free PMC article.
344 results