Chazin WJ - Search Results

1

The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10.

Paulson CN, John K, Baxley RM, Kurniawan F, Orellana K, Francis R, Sobeck A, Eichman BF, Chazin WJ, Aihara H, Georg GI, Hawkinson JE, Bielinsky AK. Paulson CN, et al. Among authors: chazin wj. Open Biol. 2019 Aug 30;9(8):190117. doi: 10.1098/rsob.190117. Epub 2019 Aug 14. Open Biol. 2019. PMID: 31409229 Free PMC article.

2

Structural basis for DNA binding by replication initiator Mcm10.

Warren EM, Vaithiyalingam S, Haworth J, Greer B, Bielinsky AK, Chazin WJ, Eichman BF. Warren EM, et al. Among authors: chazin wj. Structure. 2008 Dec 10;16(12):1892-901. doi: 10.1016/j.str.2008.10.005. Structure. 2008. PMID: 19081065 Free PMC article.

3

Physical interactions between Mcm10, DNA, and DNA polymerase alpha.

Warren EM, Huang H, Fanning E, Chazin WJ, Eichman BF. Warren EM, et al. Among authors: chazin wj. J Biol Chem. 2009 Sep 4;284(36):24662-72. doi: 10.1074/jbc.M109.020438. Epub 2009 Jul 16. J Biol Chem. 2009. PMID: 19608746 Free PMC article.

4

Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif.

Robertson PD, Chagot B, Chazin WJ, Eichman BF. Robertson PD, et al. Among authors: chazin wj. J Biol Chem. 2010 Jul 23;285(30):22942-9. doi: 10.1074/jbc.M110.131276. Epub 2010 May 19. J Biol Chem. 2010. PMID: 20489205 Free PMC article.

5

Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase.

Vaithiyalingam S, Warren EM, Eichman BF, Chazin WJ. Vaithiyalingam S, et al. Among authors: chazin wj. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13684-9. doi: 10.1073/pnas.1002009107. Epub 2010 Jul 19. Proc Natl Acad Sci U S A. 2010. PMID: 20643958 Free PMC article.

6

A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A.

Souza-Fagundes EM, Frank AO, Feldkamp MD, Dorset DC, Chazin WJ, Rossanese OW, Olejniczak ET, Fesik SW. Souza-Fagundes EM, et al. Among authors: chazin wj. Anal Biochem. 2012 Feb 15;421(2):742-9. doi: 10.1016/j.ab.2011.11.025. Epub 2011 Dec 1. Anal Biochem. 2012. PMID: 22197419 Free PMC article.

7

Sample preparation methods to analyze DNA-induced structural changes in replication protein A.

Brosey CA, Tsutakawa SE, Chazin WJ. Brosey CA, et al. Among authors: chazin wj. Methods Mol Biol. 2012;922:101-22. doi: 10.1007/978-1-62703-032-8_6. Methods Mol Biol. 2012. PMID: 22976179 Free PMC article.

8

Insights into eukaryotic primer synthesis from structures of the p48 subunit of human DNA primase.

Vaithiyalingam S, Arnett DR, Aggarwal A, Eichman BF, Fanning E, Chazin WJ. Vaithiyalingam S, et al. Among authors: chazin wj. J Mol Biol. 2014 Feb 6;426(3):558-69. doi: 10.1016/j.jmb.2013.11.007. Epub 2013 Nov 13. J Mol Biol. 2014. PMID: 24239947 Free PMC article.

9

Structural analysis of replication protein A recruitment of the DNA damage response protein SMARCAL1.

Feldkamp MD, Mason AC, Eichman BF, Chazin WJ. Feldkamp MD, et al. Among authors: chazin wj. Biochemistry. 2014 May 13;53(18):3052-61. doi: 10.1021/bi500252w. Epub 2014 Apr 30. Biochemistry. 2014. PMID: 24730652 Free PMC article.

10

Functional dynamics in replication protein A DNA binding and protein recruitment domains.

Brosey CA, Soss SE, Brooks S, Yan C, Ivanov I, Dorai K, Chazin WJ. Brosey CA, et al. Among authors: chazin wj. Structure. 2015 Jun 2;23(6):1028-38. doi: 10.1016/j.str.2015.04.008. Epub 2015 May 21. Structure. 2015. PMID: 26004442 Free PMC article.

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