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Page 1
Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties.
Hofmans S, Vanden Berghe T, Devisscher L, Hassannia B, Lyssens S, Joossens J, Van Der Veken P, Vandenabeele P, Augustyns K. Hofmans S, et al. Among authors: hassannia b. J Med Chem. 2016 Mar 10;59(5):2041-53. doi: 10.1021/acs.jmedchem.5b01641. Epub 2016 Feb 8. J Med Chem. 2016. PMID: 26696014
An outline of necrosome triggers.
Vanden Berghe T, Hassannia B, Vandenabeele P. Vanden Berghe T, et al. Among authors: hassannia b. Cell Mol Life Sci. 2016 Jun;73(11-12):2137-52. doi: 10.1007/s00018-016-2189-y. Epub 2016 Apr 6. Cell Mol Life Sci. 2016. PMID: 27052312 Free PMC article. Review.
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.
Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayır H, Abhari BA, Angeli JPF, Choi SM, Meul E, Heyninck K, Declerck K, Chirumamilla CS, Lahtela-Kakkonen M, Van Camp G, Krysko DV, Ekert PG, Fulda S, De Geest BG, Conrad M, Kagan VE, Vanden Berghe W, Vandenabeele P, Vanden Berghe T. Hassannia B, et al. J Clin Invest. 2018 Aug 1;128(8):3341-3355. doi: 10.1172/JCI99032. Epub 2018 Jun 25. J Clin Invest. 2018. PMID: 29939160 Free PMC article.
Targeting Ferroptosis to Iron Out Cancer.
Hassannia B, Vandenabeele P, Vanden Berghe T. Hassannia B, et al. Cancer Cell. 2019 Jun 10;35(6):830-849. doi: 10.1016/j.ccell.2019.04.002. Epub 2019 May 16. Cancer Cell. 2019. PMID: 31105042 Free article. Review.
Ferroptosis: Biological Rust of Lipid Membranes.
Hassannia B, Van Coillie S, Vanden Berghe T. Hassannia B, et al. Antioxid Redox Signal. 2021 Aug 20;35(6):487-509. doi: 10.1089/ars.2020.8175. Epub 2020 Sep 9. Antioxid Redox Signal. 2021. PMID: 32808533 Review.
Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state.
Ghazavi F, Huysentruyt J, De Coninck J, Kourula S, Martens S, Hassannia B, Wartewig T, Divert T, Roelandt R, Popper B, Hiergeist A, Tougaard P, Vanden Berghe T, Joossens M, Berx G, Takahashi N, Wahida A, Vandenabeele P. Ghazavi F, et al. Among authors: hassannia b. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2024508119. doi: 10.1073/pnas.2024508119. Proc Natl Acad Sci U S A. 2022. PMID: 35105800 Free PMC article.
Targeting ferroptosis protects against experimental (multi)organ dysfunction and death.
Van Coillie S, Van San E, Goetschalckx I, Wiernicki B, Mukhopadhyay B, Tonnus W, Choi SM, Roelandt R, Dumitrascu C, Lamberts L, Dams G, Weyts W, Huysentruyt J, Hassannia B, Ingold I, Lele S, Meyer E, Berg M, Seurinck R, Saeys Y, Vermeulen A, van Nuijs ALN, Conrad M, Linkermann A, Rajapurkar M, Vandenabeele P, Hoste E, Augustyns K, Vanden Berghe T. Van Coillie S, et al. Among authors: hassannia b. Nat Commun. 2022 Feb 24;13(1):1046. doi: 10.1038/s41467-022-28718-6. Nat Commun. 2022. PMID: 35210435 Free PMC article.
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